Selenium, selenoproteins and neurodegenerative diseases

Cardoso, Bárbara Rita; Roberts, Blaine R.; Bush, Ashley I.; Hare, Dominic J.

doi:10.1039/c5mt00075k

Cited by 224 publications

(139 citation statements)

References 192 publications

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“…Trace minerals efficacy on the immune response lies mainly in the functions of zinc (Liao et al., ; Park, Birkhold, Kubena, Nisbet, & Ricke, ; Sato, Listar, & Bonamin, ) and selenium (Cardoso, Roberts, Bush, & Hare, ). However, CAFQ inclusion did not showed any benefits over antibody titres, which is in line with what has been reported in some studies from laying hens (Lim & Paik, ; Manangi et al, ).…”

Section: Discussionmentioning

confidence: 99%

Organic trace minerals on productive performance, egg quality and immune response in Bovans White laying hens

Ramos-Vidales

Gómez-Verduzco

Cortés-Cuevas

et al. 2019

Animal Physiology Nutrition

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This study was performed in 360 laying Bovans White hens and aimed to evaluate the effect of Carbo‐Amino‐Phosphate‐Chelates (CAFQ) as a mineral premix and its 30% reduction by compared to inorganic trace minerals (ITM) concerning its performance, egg quality, tibia breaking strength and immunity. Sixty‐week‐old hens were assigned into three treatments with 10 replicates of 12 birds each. Treatments were as follows: (a) (100% ITM), (b) (100% CAFQ) and (c) (70% CAFQ). Based on the results obtained during 12 weeks, under the current test conditions, improved yolk colour (p < 0.05); shell breaking strength (p < 0.05); and storage time (p < 0.05) were observed in hens fed with a diet reduced by 70% in CAFQ inclusion showed similar performance behaviour and better egg breaking strength regarding with ITM, suggesting the possibility of minimizing the inclusion of trace minerals in laying hen diets improving environmental impact, in contrast to the use of inorganic sources of minerals.

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Section: Discussionmentioning

confidence: 99%

Organic trace minerals on productive performance, egg quality and immune response in Bovans White laying hens

Ramos-Vidales

Gómez-Verduzco

Cortés-Cuevas

et al. 2019

Animal Physiology Nutrition

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“…Selenium is also maintained in its organic form (like selenomethionine and selenocysteine) via selenocysteine lysis activity or trans-selenation. These activities are required for selenide production, and selenium, which is a substrate for SEPHS2 , is required for conversion into selenophosphate, a selenium donor in selenoprotein synthesis (Cardoso et al, 2015; Veres et al, 1994). The 40-fold plus upregulation of SEPHS2 at the fast feeding stage and significantly high selenium levels in blood-fed ticks suggest there is high sele-nophosphate synthesis.…”

Section: Discussionmentioning

confidence: 99%

Amblyomma maculatum SECIS binding protein 2 and putative selenoprotein P are indispensable for pathogen replication and tick fecundity

Budachetri

Crispell

Karim

2017

Insect Biochemistry and Molecular Biology

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Selenium, a vital trace element, is incorporated into selenoproteins to produce selenocysteine. Our previous studies have revealed an adaptive co-evolutionary process that has enabled the spotted fever-causing tick-borne pathogen Rickettsia parkeri to survive by manipulating an antioxidant defense system associated with selenium, which includes a full set of selenoproteins and other antioxidants in ticks. Here, we conducted a systemic investigation of SECIS binding protein 2 (SBP2) and putative selenoprotein P (SELENOP) by transcript silencing in adult female Gulf-coast ticks (Amblyomma maculatum). Knockdown of the SBP2 and SELENOP genes depleted the respective transcript levels of these tick selenogenes, and caused differential regulation of other antioxidants. Importantly, the selenium level in the immature and mature tick stages increased significantly after a blood meal, but the selenium level decreased in ticks after the SBP2 and SELENOP knockdowns. Moreover, the SBP2 knockdown significantly impaired both transovarial transmission of R. parkeri to tick eggs and egg hatching. Overall, our data offer new insight into the relationship between the SBP2 selenoprotein synthesis gene and the putative tick SELENOP gene. It also augments our understanding of selenoprotein synthesis, selenium maintenance and utilization, and bacterial colonization of a tick vector.

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“…In addition, selenium proteins, as MARRS receptor (Schütze et al 1998), can promote the cell proliferation (Zeng 2009;Zhang et al 2013), and, on the other side, regulate the reduction of CENP that mediates mitotic progress (Cardoso et al 2015), with the heat shock proteins (HSP) acting upon transcription (Kochupillai 2008). Then, MRPs are encoded by nuclear genes, are synthesized in the cytosol, and are then imported into mitochondria for assembly (Zhang et al 2015).…”

Section: Mapk Signaling Pathway In Callus Proliferation During the Camentioning

confidence: 99%

Signaling pathway in development of Camellia oleifera nurse seedling grafting union

Feng

Yang

Chen

et al. 2017

Trees

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Key message The anatomical and physiological signaling pathways associated with successful scion-rootstock union in nurse seedling grafting of Camellia oleifera propagation are illustrated. Abstract Grafting, the successful union between scion and rootstock, has practical and biological importance. Nurse seedling grafting, as those practiced for Camellia oleifera, often results in high cell division activity and affinity, and is usually associated with significant rootstock and scion anatomical structures changes. However, a comprehensive explanation of signaling pathways, and how they affect graft union development, is still largely unknown. The present study investigates the union formation process in C. oleifera nurse seedling grafts and determines that it consists of six stages, namely, isolation layer formation, rootstock callus differentiation, scion callus differentiation, callus proliferation and connection, cambium differentiation and connection, and conducting tissue differentiation and connection, extending over a period of 35 days. Principal components analyses of the observed changes in physiology and protein expression identified three main factors contributing to the union formation process: cell proliferation, cell differentiation, and vascular bundle development. Further analysis showed that the regulation of the union formation process can be divided into two signaling pathways, namely, calcium and MAPK, which occur during vascular bundle development and cell proliferation and differentiation, respectively.

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Selenium, selenoproteins and neurodegenerative diseases

Cited by 224 publications

References 192 publications

Organic trace minerals on productive performance, egg quality and immune response in Bovans White laying hens

Organic trace minerals on productive performance, egg quality and immune response in Bovans White laying hens

Amblyomma maculatum SECIS binding protein 2 and putative selenoprotein P are indispensable for pathogen replication and tick fecundity

Signaling pathway in development of Camellia oleifera nurse seedling grafting union

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