Selenium

New Perspectives on Selenium and Selenoproteins in Cardiomyopathy

“…Moreover, several polymorphisms in SELENOP gene are associated with susceptibility of tumors viz. breast cancer, colorectal cancer and prostate cancer [1].…”

“…They may do so through several mechanisms that are discombobulated in cardiomyopathy including maintaining healthy mitochondria, redox regulation, antiinflammatory effects, improving immune cell functionality, improve thyroid metabolism and reducing ER stress. Selenium (Se) is an indispensable micronutrient for a number of biologic processes, being integrated as a selenocystein in the primary structure of selenoproteins [1]. Strikingly, Se deficiency has been well recognized as a contributing factor to pathological conditions including heart disease, neuromuscular disorders, cancer, male infertility, inflammation and other disorders [1].…”

“…Selenium (Se) is an indispensable micronutrient for a number of biologic processes, being integrated as a selenocystein in the primary structure of selenoproteins [1]. Strikingly, Se deficiency has been well recognized as a contributing factor to pathological conditions including heart disease, neuromuscular disorders, cancer, male infertility, inflammation and other disorders [1].…”