Selenium and the impact of its supplementation on subclinical hypothyroidism

Abstract

Hypothyroidism is a common disease, very often associated with an autoimmune reaction of the body leading to lymphocytic infiltration within the thyroid gland, i.e. Hashimoto's disease. In the classification of disease entities involving the functioning of the thyroid gland, subclinical hypothyroidism can also be distinguished - a condition in which peripheral thyroid hormone concentrations are within normal limits, but as a result of the inhibition of negative feedback loops, the TSH value increases. The subject of this paper is the consideration of the potential impact of selenium supplementation - an element included in bioactivators associated with the thyroid gland, responsible, among others, for the production of an active form of thyroid hormones, for the possibility of achieving euthyroidism in patients with subclinical hypothyroidism, using only rational selenium supplementation, without the use of exogenous thyroid hormones.

Skin appendage abnormalities in hypothyroidism: understanding and management

“…Additionally, TPO antibody levels decreased in both patients who responded to selenium supplementation and the remaining participants in the study group. [11] Concomitant diseases of hypothyroidism The autoimmune aetiology of most cases of primary hypothyroidism predisposes patients with hypothyroidism to a higher likelihood of experiencing other related disorders, such as type 1 diabetes, adrenal insufficiency, premature menopause, inflammatory bowel diseases, rheumatic diseases, gluten enteropathy, multiple sclerosis, or vitiligo. Another indication may be a significant family history, as the propensity for thyroid disorders, including autoimmune hypothyroidism, often runs in families.…”