Selectivity of attenuation (i.e., gating) of somatosensory potentials during voluntary movement in humans

Tapia, Maria C.; Cohen, Leo G.; Starr, Arnold

doi:10.1016/0168-5597(87)90031-1

Cited by 80 publications

(36 citation statements)

References 18 publications

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“…As in previous studies of either afferent or efferent gating (Abbruzzese et al 1980(Abbruzzese et al , 1981Burke et al 1982;Cohen and Starr 1987;Hsieh et al 1995;Insola et al 2004;Jones et al 1989;Klostermann et al 2002a;Tapia et al 1987), there were no changes in the latencies of any subcortical or cortical responses, nor in the amplitude of the braquial plexus response (N9), indicating that the gating effect is mediated only by central structures. In particular, an interaction between lemniscal and spinocerebellar inputs has been suggested to occur at a thalamic level Okajima et al 1991).…”

Section: Interactions Between Muscle and Cutaneous Afferent Volleyssupporting

confidence: 51%

Subcortical Interactions Between Somatosensory Stimuli of Different Modalities and Their Temporal Profile

Costa¹,

Valls‐Solé²,

Valldeoriola³

et al. 2008

Journal of Neurophysiology

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Costa J, Valls-Solé J, Valldeoriola F, Rumià J. Subcortical interactions between somatosensory stimuli of different modalities and their temporal profile. J Neurophysiol 100: 1610 -1621, 2008. First published July 2, 2008 doi:10.1152/jn.90412.2008. Interactions between inputs of different sensory modality occur along the sensory pathway, including the thalamus. However, the temporal profile of such interaction has not been fully studied. In eight patients who had been implanted an intrathalamic electrode for deep brain stimulation as symptomatic treatment of tremor, we investigated the interactions between mechanical taps and electrical nerve stimuli. Somatosensory evoked potentials (SEPs) were recorded from Erb's point, cervical spinal cord, nucleus ventrointermedialis of the thalamus, and parietal cortex. A handheld electronic reflex hammer was used to deliver a mechanical tap to the skin overlying the first dorsal interosseous muscle and to trigger an ipsilateral digital median nerve electrical stimulus time-locked to the mechanical tap with a variable delay of 0 to 50 ms. There were significant time-dependent interactions between the two sensory volleys at the subcortical level. Thalamic SEPs were decreased in amplitude at interstimulus intervals (ISIs) from 10 to 40 ms with maximum effect at 20 ms (Ϫ42.8 Ϯ 10.5%; P Ͻ 0.001). A similar decrease was also seen in the number and frequency of the high-frequency components of thalamic SEPs (Ϫ25 Ϯ 4%). A smaller reduction (Ϫ18.1 Ϯ 5.8%; P Ͻ 0.001) was present in upper cervical response at ISI ϭ 20 ms. There were no changes in peripheral responses. Cortical SEPs were almost completely absent in some subjects at ISIs from 20 to 50 ms. There were no changes in SEP latencies. Our results indicate that significant time-dependent interactions between sensory volleys occur at the subcortical level. These observations provide further insight into the physiological mechanisms underlying afferent gating between sensory volleys of different modality.

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Section: Interactions Between Muscle and Cutaneous Afferent Volleyssupporting

confidence: 51%

Subcortical Interactions Between Somatosensory Stimuli of Different Modalities and Their Temporal Profile

Costa¹,

Valls‐Solé²,

Valldeoriola³

et al. 2008

Journal of Neurophysiology

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“…Gating accompanying both the preparation and the act of movement can be accompanied by an attenuation of sensory processes occurring both before and during the motor activity (Starr et al, 1969;Starr and Cohen, 1985). Gating in the auditory system has been shown to be due to both an attenuation of acoustic input accompanying movementrelated contractions of middle ear muscles (Cannel and Starr, 1963) and to changes in central auditory pathway processing (Starr, 1964;Tapia et al, 1987). We do not consider gating to be a mechanism accounting for the attenuation of any of the components defined in this study.…”

Section: Processes Acting To Modulate Evoked Potentialsmentioning

confidence: 99%

Sequential changes of auditory processing during target detection: motor responding versus mental counting

Starr

Aguinaldo

Roe

et al. 1997

Electroencephalography and Clinical Neurophysiology/Electromyog

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“…SI activity is attenuated by other interfering somatosensory stimuli, but only very selectively when they occur anatomically near. 29 For instance, stimulation of the index finger produces SI activity that is attenuated with a second competitive stimulus occurring on the same hand but not the opposite one. 30 Interesting observations from the present data were the parallels between the early SEP components and the changes in perceptual thresholds.…”

Section: Staines Et Al Sensory Gating and Stroke Recovery 2649mentioning

confidence: 99%

Somatosensory Gating and Recovery From Stroke Involving the Thalamus

Staines

Black

Graham

et al. 2002

Stroke

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Background and Purpose-In the undamaged brain, sensory input to the cortex is intricately controlled via sensory gating mechanisms. Given the role of corticothalamic pathways in this control, it was hypothesized that in patients recovering from thalamic stroke there would be evidence of disrupted sensory gating and that efficient control of cortical sensory inputs would emerge during recovery. Methods-Four patients were tested serially after stroke from 1 to 24 weeks after injury. Perceptual thresholds, somatosensory evoked potential amplitudes, and functional MRI activations under specific somatosensory stimulation conditions were measured. Results-All patients demonstrated comparable results, revealing disrupted threshold detection to vibrotactile stimuli in the presence of a concurrent competing, contralateral input. In contrast, threshold detection was comparable between the affected and unaffected sides when there were no competing stimuli. This compromised capacity to inhibit competing sensory inputs was paralleled by a reduction in the measured activation of cortical representation in the stroke-affected hemisphere (functional MRI and somatosensory evoked potential) during bilateral stimulation. After recovery, perceptual detection improvements during bilateral stimulation were paralleled by enhancements of primary somatosensory cortical activation in the stroke-affected hemisphere. Conclusions-These results provide insight into potential mechanisms that contribute to sensory gating and suggest that the ability to control sensory input through effective gating mechanisms, in addition to primary somatosensory representation, may be important for poststroke sensory recovery.

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Selectivity of attenuation (i.e., gating) of somatosensory potentials during voluntary movement in humans

Cited by 80 publications

References 18 publications

Subcortical Interactions Between Somatosensory Stimuli of Different Modalities and Their Temporal Profile

Subcortical Interactions Between Somatosensory Stimuli of Different Modalities and Their Temporal Profile

Sequential changes of auditory processing during target detection: motor responding versus mental counting

Somatosensory Gating and Recovery From Stroke Involving the Thalamus

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