Selectivity and random‐access in automatic analysers

Bonini, Pierangelo; Ceriotti, Ferruccio; Franzini, Carlo

doi:10.1155/s1463924688000343

Cited by 6 publications

(2 citation statements)

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“…Objective analytical performance evaluations are important to clinical laboratories when looking at the selection of new instruments [1][2][3][4]. The BM/Hitachi 911 is a very recent selective access analyser from Boehringer Mannheim GmbH.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a random access analyser: BM/Hitachi 911

Kanluan

Tangvarasittichai

1995

Journal of Analytical Methods in Chemistry

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The performance of Boehringer Mannheim's BM/Hitachi 911 was evaluated for three months. The mean coeffcient of variation (CV) of the within-run and between-run imprecision of the 16 analytes were less than 1.16% (range 0.47-2.38%) and 1.35% (range 0.62-2.93,%), respectively. A linearity study for the various assays covered clinically important levels. No relevant drift was observed during an eight-hour assay nor was any sample-related carry-over detected. In all cases, the regression analyses (slopes) of the results obtainedfrom BM/Hitachi 911 and 717 were between the extreme values of 0.94 and 1.05. During the three months of operation, no major problem was encountered. The BM/Hitachi 911 was found to be easily operated, to require minimal attention and simple daily maintenance during operation.

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Section: Introductionmentioning

confidence: 99%

Evaluation of a random access analyser: BM/Hitachi 911

Kanluan

Tangvarasittichai

1995

Journal of Analytical Methods in Chemistry

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“…In recent years, random access analysers have attracted considerable interest among clinical chemists in smallto medium-sized laboratories because of their obvious advantages with regard to flexibility, immediate readiness and reliability [1,2]. The random access analyser COBAS MIRA S is an extended version of the wellknown COBAS MIRA [3].…”

Section: Introductionmentioning

confidence: 99%

Laboratory evaluation of the COBAS MIRA S random access analyser

Kanluan

Intaramanee

Tangvarasittichai

et al. 1991

Journal of Analytical Methods in Chemistry

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The random access analyser COBAS MIRA S (Roche Diagnostics) was evaluated for two months. The instrument is a computer-controlled discrete analyser which can be run in a combination profile and single test mode. This instrument has special features, including an automatic cuvette segment changer, a reagent rack cooling system, an external keyboard and monitor, as well as a bar-code facility for the entry of test parameters, worklists and sample identification numbers. Study of within-run and between-run precision gave values of % CV 0.54-3.37 and 0.61-3.65, respectively, for a variety of assays. Linearity testing to the upper limit of each test was also studied and were found to cover the necessary pathological range. Within the two-month period, no major problems were encountered. The instrument required minimum operator attention during operation. Correlation studies with the Hitachi 705 using six clinical chemistry tests (glucose, cholesterol, triglyceride, ALP, AST, ALT) gave correlation coefficients ranging from 0.95-0.99 and slopes of 0.91-1.17.

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