Selective Voronoi tessellation as a method to design anisotropic and biomimetic implants

Deering, Joseph; Dowling, Kierdra I.; DiCecco, Liza‐Anastasia; McLean, Griffin D.; Yu, Bosco; Grandfield, Kathryn

doi:10.1016/j.jmbbm.2021.104361

Cited by 39 publications

(21 citation statements)

References 46 publications

(58 reference statements)

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“…Nonetheless, mechanical anisotropy is an inherent attribute of biological materials. Hence, biomimetic structures attempting to imitate the behavior of bone tissue should also exhibit comparable anisotropy [ 59 , 60 ].…”

Section: Testing Results and Discussionmentioning

confidence: 99%

Additive Manufacturing and Mechanical Characterization of PLA-Based Skull Surrogates

et al. 2022

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Several occupational and leisure activities involve a high risk of head impacts, resulting in varying degrees of injuries with chronic consequences that adversely affect life quality. The design and manufacturing of effective head protections rely on proper head simulators to mimic the behavior to impact loading. 3D-printed human skulls are reported herein to address the need for reproducible, cost-effective, anatomically-correct surrogates. To demonstrate the viability of the investigated approach, surrogate bone sections and skulls were mechanically tested under quasi-static loading conditions. The 3D-printed bone sections were flexural tested, elucidating the effect of printing orientations and the sample geometry on their mechanical behavior. The printing orientation minimally influenced the results due to the high infill percentage, while the sample geometry played a major role in the flexural properties because of the change in the section properties. The surrogate skulls were submitted to lateral compression and frontal penetration tests to assess the impact of the sectioning strategy on the overall mechanical performance. Results indicate that PLA-based surrogates reasonably reproduce the behavior of skulls. In addition, the sectioning strategy elucidated the effect of skull sutures, while streamlining the additive manufacturing process. The outcomes lay the foundation for future research seeking a complete surrogate head.

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Section: Testing Results and Discussionmentioning

confidence: 99%

Additive Manufacturing and Mechanical Characterization of PLA-Based Skull Surrogates

et al. 2022

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“…Furthermore, all computational models are tunable to provide a degree of anisotropy that is in a similar range to trabecular bone structure. It is also likely that these structures could prove useful in tissue engineering applications, whereby scaffolds can be created through additive manufacturing (Deering et al, 2021). In these applications, the structures presented here could be tailed for mechanical properties and also hydraulic parameters, such as porosity and permeability, which can be of interest to ensure sufficient permeability for cell and tissue in-growth.…”

Section: Discussionmentioning

confidence: 99%

“…This limits their applicability when trying to understand trabecular bone mechanics, and also could limit their application in designing biomimetic structures (Kang et al, 2020) produced through additive manufacturing e.g. for applications that include bone substitutes, scaffolds (Rammohan et al, 2015;Rammohan and Tan, 2016;Timercan et al, 2021;Yánez et al, 2016), and porous implants (Deering et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

A morphological, topological and mechanical investigation of gyroid, spinodoid and dual-lattice algorithms as structural models of trabecular bone

Vafaeefar

Moerman²,

Kavousi³

et al. 2023

Journal of the Mechanical Behavior of Biomedical Materials

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“…A more biomimetic approach is given in Deering et al [3]: Here, porous scaffolds are proposed to mimic the natural structure of trabecular bone by using Voronoi tessellation with selective seeding. Stress shielding effects, where an implant's high stiffness results in a stiffness discrepancy between surrounding bone and the implant, are an important factor for osseointegration.…”

Section: Additive Manufacturingmentioning

confidence: 99%

On the Structural Properties of Voronoi Diagrams

2021

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A Voronoi diagram is a tessellation technique, which subdivides space into regions in proximity to a given set of objects called seeds. Patterns emerging naturally in biological processes (for example, in cell tissue) can be modelled in a biomimicry process via Voronoi diagrams. As they originate in nature, we investigate the physical properties of such patterns to determine whether they are optimal given the constraints imposed by surrounding geometry and natural forces. This paper describes under what circumstances the Voronoi tessellation has optimal (structural) properties by surveying recent studies that apply this tessellation technique across different scales. To investigate the properties of random and optimized Voronoi tessellations in comparison to a regular tessellation method, we additionally run and evaluate a simulation in Karamba3D, a parametric structural engineering tool for Rhinoceros3D. The novelty of this research lies in presenting a simple and straightforward simulation of Voronoi diagrams and highlighting how and where their advantages over regular tessellations can be exploited by surveying more advanced approaches as found in literature.

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Selective Voronoi tessellation as a method to design anisotropic and biomimetic implants

Cited by 39 publications

References 46 publications

Additive Manufacturing and Mechanical Characterization of PLA-Based Skull Surrogates

Additive Manufacturing and Mechanical Characterization of PLA-Based Skull Surrogates

A morphological, topological and mechanical investigation of gyroid, spinodoid and dual-lattice algorithms as structural models of trabecular bone

On the Structural Properties of Voronoi Diagrams

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