Selective separation of Bi3+ from La3+/Ac3+ by sorption on sulfonated carbon materials for use in an inverse 225Ac/213Bi radionuclide generator: Batch and column tests

225Ac/213Bi radionuclide generators for the separation of 213Bi towards clinical demands

“…, R-N(CH 3 ) 3 + , R-N(CH 2 CH 3 ) 3 + , and R-NH(CH 2 CH 3 ) 2 + ). 38,39,47,107–114 This type of interaction is highly governed by the solution pH. Typically, the surface charge of the adsorbents becomes negative when the solution pH exceeds the point of zero charges (pH pzc ), which is beneficial for the adsorption of cations.…”

“…105 Apart from the impact on the charge of the functional groups, the solution pH also influences the metal ion speciation. 47,114,115 This is because the concentration of H + ions can affect the oxidation states, solubility, ionization, and forms of metal ions. Apart from the pH, other solution parameters, including the ionic strength, and the presence of co-existing ions that can complexate, play a major role in the type of interaction.…”

Gamma radiation effects on AG MP-50 cation exchange resin and sulfonated activated carbon for bismuth-213 separation

“…Detailed information on the above characterization methods can be found in our earlier work. 27 Solid state 13 C-CPMAS (Cross Polarization Magic Angle Spinning) NMR spectra were acquired on a Jeol ECZ600R 600 MHz spectrometer (14.1 Tesla) equipped with a 3.2 mm wide VT Range HXMAS probe. MAS was performed at 20 kHz.…”

“… 4 Additionally, AG MP-50 was expected to be employed for the further purification of 213 Bi eluate in 1 mol L −1 HCl, derived from an inverse generator. 27 The impact of the radiation on the material characteristics for AG MP-50 and SAC was then examined by carrying out scanning electron microscopy (SEM) and X-ray diffraction (XRD) measurements. The identification and quantification of the chemical structures of these materials were determined by diffuse reflectance infrared Fourier transformations (DRIFT), solid-state nuclear magnetic resonance (NMR), and X-ray photoelectron spectroscopy (XPS).…”

Preparation of Medical 228Th-224Ra Radionuclide Generator Based on SiO2@TiO2 Microspheres

“…The central component inside a radionuclide generator responsible for immobilizing the parent radionuclide and releasing the daughter radionuclide is the adsorption column typically filled with functional materials. − Among all the available materials, the core–shell SiO 2 @TiO 2 microsphere, comprised of an inert SiO 2 core and an active TiO 2 shell, stands out as a significant alternative for fabricating a 228 Th- 224 Ra generator. Inorganic materials are supposed to have much higher irradiation resistance than organic resins commonly utilized in a 227 Ac- 227 Th- 223 Ra generator.…”