Selective role of lingual/parahippocampal gyrus and retrosplenial complex in spatial memory across viewpoint changes relative to the environmental reference frame

Sulpizio, Valentina; Committeri, Giorgia; Lambrey, Simon; Berthoz, Alain; Galati, Gaspare

doi:10.1016/j.bbr.2012.12.031

Cited by 94 publications

(102 citation statements)

References 74 publications

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“…The role RSC plays in these more complex processes could merely reflect the fact that they are usually centered upon permanent environmental features. RSC has also been suggested to assist in translating between and integrating egocentric and allocentric spatial information (Sherrill et al, 2013; Sulpizio, Committeri, Lambrey, Berthoz, & Galati, 2013; Vann et al, 2009; Byrne, Becker, & Burgess, 2007), but again this could similarly reflect the reliance of these processes on manipulating mainly permanent cues.…”

Section: Discussionmentioning

confidence: 99%

Dissociating Landmark Stability from Orienting Value Using Functional Magnetic Resonance Imaging

Auger

Maguire

2018

Journal of Cognitive Neuroscience

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Retrosplenial cortex (RSC) plays a role in using environmental landmarks to help orientate oneself in space. It has also been consistently implicated in processing landmarks that remain fixed in a permanent location. However, it is not clear whether the RSC represents the permanent landmarks themselves or instead the orienting relevance of these landmarks. In previous functional magnetic resonance imaging (fMRI) studies, these features have been conflated—stable landmarks were always useful for orienting. Here, we dissociated these two key landmark attributes to investigate which one best reflects the function of the RSC. Before scanning, participants learned the features of novel landmarks about which they had no prior knowledge. During fMRI scanning, we found that the RSC was more engaged when people viewed permanent compared with transient landmarks and was not responsive to the orienting relevance of landmarks. Activity in RSC was also related to the amount of landmark permanence information a person had acquired and, as knowledge increased, the more the RSC drove responses in the anterior thalamus while viewing permanent landmarks. In contrast, the angular gyrus and the hippocampus were engaged by the orienting relevance of landmarks, but not their permanence, with the hippocampus also sensitive to the distance between relevant landmarks and target locations. We conclude that the coding of permanent landmarks in RSC may drive processing in regions like anterior thalamus, with possible implications for the efficacy of functions such as navigation.

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Section: Discussionmentioning

confidence: 99%

Dissociating Landmark Stability from Orienting Value Using Functional Magnetic Resonance Imaging

Auger

Maguire

2018

Journal of Cognitive Neuroscience

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“…Adaptation effects to place, view, and heading were found in a unexpectedly large set of regions, in particular in the fronto-parietal cortex (pIPS, SMG, FEF, IFG: Figure 2C); many of these regions also showed an adaptation effect proportional to spatial distances (Figures 4A,B, left column). It is particularly surprising to find such effects in parieto-frontal regions, which are known to be crucial for egocentric spatial representations (Committeri et al, 2004; Sulpizio et al, 2013; see also Galati et al, 2010 for a review). One possible interpretation, which we develop below, is that adaptation effects in parieto-frontal cortex reflect a process of egocentric updating of spatial locations rather than a true allocentric encoding of places and views.…”

Section: Discussionmentioning

confidence: 99%

“…In each imaging run, participants passively viewed eight alternating blocks (16 s) of photographs of faces and places/scenes presented for 300 ms every 500 ms, interleaved with fixation periods of 15 s on average (see Sulpizio et al, 2013). During each run we acquired 234 functional MR volumes, for a total of 7 min each.…”

Section: Methodsmentioning

confidence: 99%

“…Accordingly, view cells have been discovered in the human parahippocampal gyrus through intracranial recordings (Ekstrom et al, 2003). RSC is active during real and imagined navigation (Ino et al, 2002; Wolbers and Büchel, 2005), retrieval of environment-centered information (Committeri et al, 2004; Galati et al, 2010; Sulpizio et al, 2013), and in the presence of permanent items within the scene (Auger et al, 2012; Auger and Maguire, 2013). Although several imaging studies reported the involvement of the hippocampus in spatial navigation and/or map-like representations (Ghaem et al, 1997; Maguire et al, 1998; Wolbers and Büchel, 2005; Iaria et al, 2007; Wolbers et al, 2007; Baumann et al, 2010, 2012; Brown et al, 2010, 2012; Morgan et al, 2011; Viard et al, 2011; Baumann and Mattingley, 2013; Brown and Stern, 2014), the discovery of place cells in intracranial recordings in the human hippocampus represents the most direct evidence of a place representation in the human brain (Ekstrom et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

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Distributed cognitive maps reflecting real distances between places and views in the human brain

Sulpizio

Committeri

Galati

2014

Front. Hum. Neurosci.

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Keeping oriented in the environment is a multifaceted ability that requires knowledge of at least three pieces of information: one’s own location (“place”) and orientation (“heading”) within the environment, and which location in the environment one is looking at (“view”). We used functional magnetic resonance imaging (fMRI) in humans to examine the neural signatures of these information. Participants were scanned while viewing snapshots which varied for place, view and heading within a virtual room. We observed adaptation effects, proportional to the physical distances between consecutive places and views, in scene-responsive (retrosplenial complex and parahippocampal gyrus), fronto-parietal and lateral occipital regions. Multivoxel pattern classification of signals in scene-responsive regions and in the hippocampus allowed supra-chance decoding of place, view and heading, and revealed the existence of map-like representations, where places and views closer in physical space entailed activity patterns more similar in neural representational space. The pattern of hippocampal activity reflected both view- and place-based distances, the pattern of parahippocampal activity preferentially discriminated between views, and the pattern of retrosplenial activity combined place and view information, while the fronto-parietal cortex only showed transient effects of changes in place, view, and heading. Our findings provide evidence for the presence of map-like spatial representations which reflect metric distances in terms of both one’s own and landmark locations.

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“…The superior frontal and lingual gyrus have been reported [24] [29]- [32] as important structures associated with self-intended actions. The precuneus is a structure considered as a hub connecting the parietal and prefrontal regions [33] [34], and thereby plays an important role in various functions, including retrospective, episodic and autobiographic memories [7] and self reasoning [7] [10] [27]. Many of the sources discriminating NA from YA are located in the superior frontal, fusiform and lingual regions as well as in the precuneus, supporting the hypothesis that self-related circuits are important in establishing NA truth.…”

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confidence: 99%

Brain and Law: An EEG Study of How We Decide or Not to Implement a Law

Rocha¹,

Massad²,

Rocha³

et al. 2014

JBBS

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Brazil has introduced a referendum regarding the prohibition of firearm commerce and propaganda arguments have invoked socially and personally driven issues in the promotion of voting in favor of and against firearm control, respectively. Here, we used different techniques to study the brain activity associated with a voter's perception of the truthfulness of these arguments and their influence on voting decisions. Low-resolution tomography was used to identify the possible different sets of neurons activated in the analysis of the different types of propaganda. Linear correlation was used to calculate the amount information ( ) i H e provided to different electrodes about how these sets of neurons enroll themselves to carry out this cognitive analysis. The results clearly showed that vote decision was not influenced by arguments that were introduced by propaganda, which was typically driven by specific social or self-interest motives. However, different neural circuits were identified in the analysis of each type of propaganda argument, independently of the declared vote (for or against the control) intention.

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Selective role of lingual/parahippocampal gyrus and retrosplenial complex in spatial memory across viewpoint changes relative to the environmental reference frame

Cited by 94 publications

References 74 publications

Dissociating Landmark Stability from Orienting Value Using Functional Magnetic Resonance Imaging

Dissociating Landmark Stability from Orienting Value Using Functional Magnetic Resonance Imaging

Distributed cognitive maps reflecting real distances between places and views in the human brain

Brain and Law: An EEG Study of How We Decide or Not to Implement a Law

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