Selective Reduction of Nitro Compounds With Titanium(II) Reagents

George, James Baben; Chandrasekaran, Srinivasan

doi:10.1080/00397918308081828

Cited by 46 publications

(6 citation statements)

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“…Among other reagents we can also mention are Al-NiCl 2 ·6H 2 O-THF [2], titanium (II) [3] and titanium (III) [4] derivatives, FeCl 3 ·6H 2 O-H 2 N-N(CH 3 ) 2 [5], AlH 3 -AlCl 3 , formic acid and Pd-C [6]. …”

Section: Resultsmentioning

confidence: 99%

Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones

2005

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Section: Resultsmentioning

confidence: 99%

Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones

2005

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“…This was attributed to the electron withdrawing nature of all three functional groups on the aromatic ring in compound 6a and 6c including the nitro group. However, the nitro group on the aromatic ring can be selectively reduced SnCl 2 38 in anhydrous ethanol without affecting the other functional groups [39][40][41][42] to produce fluorescent compounds 6b (20 mg, 0.05 mmol, 71%) and 6d (quantitative yield).…”

Section: Resultsmentioning

confidence: 99%

Synthesis and characterization of biotin derivatives as multifunctional oligosaccharide tags

Chindarkar¹,

Franz²

2008

Arkivoc

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“…Low-valent titanium reagent makes it simple to convert nitro compounds to amines. [30] In addition to the release of Ti (II) species, this reduction reaction may also result in the formation of intermediate amines (Scheme 13). It was then combined with carbonyl compounds to produce an imine intermediate that was subsequently cyclized in order to accomplish the desired 1,2-dihydroimidazo[1,2-c]quinazolines.…”

Section: Metal Assisted Synthetic Protocolmentioning

confidence: 99%

An Extensive Analysis of Current Synthetic Methodologies and Applications of Imidazo/Benzimidazo[1,2‐c]Quinazolines

Bairy,

Sinha

2024

ChemistrySelect

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A great deal of attention has been received on developing N‐heterocyclic compounds due to their ambitious biological activities. Many of them are essential footstep to the development and discovery of new drugs. Imidazole/benzimidazole and quinazoline are essential pharmacologically active N‐heterocycles, and one of the molecular framework built up from their combination, imidazo/benzimidazo[1,2‐c]quinazoline, is of great attention in terms of synthesis, reactions, and medicinal applications. The positional variation of hetero N‐atoms and the functional groups acting as substituents in the main scaffold have a direct impact on the properties of imidazo/benzimidazo[1,2‐c]quinazolines. In addition to its physiological activities, this moiety is useful for electrical conductivity, molecules/ions sensing, coordination complex and coordination polymer (CP) formation, and their diverse applications. The major objective of this review is to highlight various synthetic approaches for imidazo/benzimidazo[1,2‐c]quinazolines motif since 2000. Toxicant‐free reaction conditions and the use of an extensive range of inexpensive substrates are two of the main practical benefits of the protocol in accomplishing the sustainable development goals.

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Selective Reduction of Nitro Compounds With Titanium(II) Reagents

Cited by 46 publications

References 3 publications

Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones

Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones

Synthesis and characterization of biotin derivatives as multifunctional oligosaccharide tags

An Extensive Analysis of Current Synthetic Methodologies and Applications of Imidazo/Benzimidazo[1,2‐c]Quinazolines

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