Selective Laser Sintering of Hydroxyapatite Reinforced Polyethylene Composites for Bioactive Implants and Tissue Scaffold Development

Hao, Liang; Savalani, M. M.; Zhang, Y; Tanner, K.E.; Harris, Russell A.

doi:10.1243/09544119jeim67

Cited by 95 publications

(65 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some groups were able to directly fabricate bioceramic bone implants using an experimental SLS system [2,3], however, to process bioceramics a thermoplastic polymer functioning as a binder material is usually required, as the lasers used in typical commercial SLS systems are unable to fuse ceramic particles together. Several biocompatible polymers have been used for SLS fabrication of scaffolds, including polyethylene, polyetheretherketone, polycaprolactone, polylactide glycolide, polyvinyl alcohol and their composites with hydroxyapatite and other bioceramics [4][5][6][7][8][9][10][11][12]. However, much of this research has only demonstrated the feasibility of fusing powder particles together, and not the fabrication of complex predesigned 3D structures.…”

Section: Introductionmentioning

confidence: 99%

Selective laser sintering of hydroxyapatite/poly-ε-caprolactone scaffolds

et al. 2010

View full text Add to dashboard Cite

Selective laser sintering (SLS) enables the fabrication of complex geometries with the intricate and controllable internal architecture required in the field of tissue engineering. In this study hydroxyapatite and poly--caprolactone, considered suitable for hard tissue engineering purposes, were used in a weight ratio of 30:70. The quality of the fabricated parts is influenced by various process parameters. Among them Four parameters, namely laser fill power, outline laser power, scan spacing and part orientation, were identified as important. These parameters were investigated according to a central composite design and a model of the effects of these parameters on the accuracy and mechanical properties of the fabricated parts was developed. The dimensions of the fabricated parts were strongly dependent on the manufacturing direction and scan spacing. Repeatability analysis shows that the fabricated features can be well reproduced. However, there were deviations from the nominal dimensions, with the features being larger than those designed. The compressive modulus and yield strength of the fabricated microstructures with a designed relative density of 0.33 varied between 0.6 and 2.3 and 0.1 and 0.6 MPa, respectively. The mechanical behavior was strongly dependent on the manufacturing direction.

show abstract

Section: Introductionmentioning

confidence: 99%

Selective laser sintering of hydroxyapatite/poly-ε-caprolactone scaffolds

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Composite materials (Ti/Al 3003) and Al 3003 matrix material were used to Table 6 [63,[67][68][69][70].…”

Section: Structural Compositesmentioning

confidence: 99%

Design for additive manufacturing of composite materials and potential alloys: a review

Hegab

2016

Manufacturing Rev.

View full text Add to dashboard Cite

-As a first step of applying additive manufacturing (AM) technology, plastic prototypes have been produced using various AM Process such as Fusion Deposition Modeling (FDM), Stereolithography (SLA) and other processes. After more research and development, AM has become capable of producing complex net shaped in materials which can be used in applicable parts. These materials include metals, ceramics, and composites. Polymers and metals are considered as commercially available materials for AM processes; however, ceramics and composites are still considered under research and development. In this study, a literature review on design for AM of composite materials and potential alloys is discussed. It is investigated that polymer matrix, ceramic matrix, metal matrix, and fiber reinforced are most common composites through AM. Furthermore, Functionally Graded Materials (FGM) is considered as an effective application of AM because AM offers the ability to control the composition and optimize the properties of the built part. An example of FGM through using AM technology is the missile nose cone which includes an ultra-high temperature ceramic graded to a refractory metal from outside to inside and it used for sustaining extreme external temperatures. During this work, different applications of AM on different classifications of composite materials are shown through studying of industrial objective, the importance of application, processing, results and future challenges.

show abstract

“…Hydroxyapatide (HA), for instance, is known for its bioactive behaviour and osteoconductivity. HA has been blended with PCL, PE, PEEK, and polyvinylalcohol (PVA), and the compound powders have been processed via laser sintering [6,7,13,14].…”

Section: Compositesmentioning

confidence: 99%

“…It appeared that this was rather due to the high HA content than to the nature of the composite powder, as in this case the HA content was 80 wt.-% and the amount of polymeric binder phase was too small to generate bonding between the particles. Maximum concentrations of hydroxyapatide (HA) in composites were investigated by Hao et al [13], Savalani et al [17], and Zhang et al [18]. Polyethylene and polyamide were used as binders, and concentrations of up to 50 % of HA were achieved.…”

Section: Compositesmentioning

confidence: 99%