Selective induction of apoptotic cell death in lung carcinoma cells by curcumin-loaded PEGylated lipid nanoparticles with minimal normal tissue toxicity: in vitro and in vivo toxicity evaluation by oral delivery

Abstract

Insufficient drug concentration, systemic toxicity to associated organs and meaningful penetration to the site of action remain the major challenge in augmenting the therapeutic efficacy against the heterogeneous disease like...