Selective enrichment of Rutin in sunscreen by boronate affinity molecularly imprinted polymer prior to determination by high performance liquid chromatography

A fluorescent sensor for rutin hydrate based on a cyanostilbene macrocycle

“…The sensing mechanism of BCM for rutin hydrate was further measured by a fluorescence Job's plot, 1 H NMR spectra and MS spectra. As shown in Fig.…”

“…This crude product was further recrystallized in DMSO/MeOH (v/v = 1 : 10) to give a white solid in 90% yield. 1…”

“…Rutin hydrate (also named 3 0 ,4 0 ,5,7-tetrahydroxyflavone-3-Drutinoside), is an activator of vitamin C in the body. [1][2][3] It exhibits a pharmacological activity and antioxidant activity profile. [4][5][6] Rutin hydrate plays an adjunctive therapeutic role in hypertensive encephalopathy, post-partum haemorrhage, retinal haemorrhage and cerebral haemorrhage, 7,8 and acts as an anti-inflammatory, antiviral, antibacterial, anticancer, antidiabetic, antiprotozoal, antiallergic, antihypertensive and immunomodulatory agent in living organisms.…”

A novel electrochemical sensor based on a molecularly imprinted polymer for highly selective and sensitive determination of rutin from herbal supplements and plant extracts

“…12 The effect of RUT on the increase in high-density lipoprotein (HDL) cholesterol and triacylglycerol levels in hyperlipidemic rats was investigated, and it was determined that RUT caused the maximum decrease in the cholesterol level. 14 When a literature review was conducted on the studies performed for RUT analysis, it was seen that the available studies are based on electrochemical nanosensors, [15][16][17][18][19][20][21][22][23][24][25][26][27] capillary electrophoresis, 28 electrochemiluminescence, 29 high-performance liquid chromatography (HPLC) with an ultraviolet (UV) detector, 8,30 HPLC with a diode array detector, 31 HPLC with chemiluminescence (CL) detection, 32 and molecularly imprinted polymer (MIP)-based electrochemical sensors. [33][34][35][36] Although the mentioned studies offer advantages such as high sensitivity for RUT determination, the most important challenges of chromatographic methods are that they require highly skilled operators, expensive equipment, and labor-intensive procedures.…”

“…6 In addition to preventing various diseases, the antioxidative effect of RUT can also be used for cosmetic purposes to protect the skin against undesired damage. 8 For the safe use of dietary supplements containing RUT, the recommended duration of use is not to exceed 12 weeks, and the daily dose is up to 600 mg. This information demonstrates that the sensitive determination of RUT in complex samples, such as plants, dietary supplements, and biological fluids, is extremely important.…”