Selective determination of dopamine in the presence of uric acid and ascorbic acid by N,N′-bis(indole-3-carboxaldimine)-1,2-diaminocyclohexane thin film modified glassy carbon electrode by differential pulse voltammetry

Uzun, Demet; Gündüzalp, Ayla Balaban; Hasdemır, Erdoğan

doi:10.1016/j.jelechem.2015.03.036

Cited by 30 publications

(13 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this way, the development of modified electrodes with high selectivity to DA has been focus of extensively work, including applications of a plenty of materials, as metal nanoparticles [9], conducting polymers [10], carbon nanotubes [11,12], graphene [4,9,10,[13][14][15], specific enzymes [16], among others. For instance, Uzun et al developed a sensor composed by N,N'-bis(indole-3-carboxaldimine)-1,2-diaminocyclohexane onto glassy carbon electrode, which is capable to separate the oxidation peaks of DA, AA and UA by the differential pulse voltammetry with limit of detection of DA equal to 0.18 mol L −1 [17]. Recently, Daniel Arulraj et al achieved very low limit of detection (20 nM) using modified GCE electrodes via electrochemical reduction of graphene oxide followed by electropolymerization of polypyrrole forming a composite film for selective determination of DA in presence of DA and UA [10].…”

Section: Introductionmentioning

confidence: 99%

Layer-by-layer composite film of nickel phthalocyanine and montmorillonite clay for synergistic effect on electrochemical detection of dopamine

Lucena

Miyazaki

Shimizu

et al. 2018

Applied Surface Science

View full text Add to dashboard Cite

a b s t r a c t Dopamine (DA) abnormal levels are related to diseases which makes important the development of fast, reliable, low-cost and sensitive devices for diagnosis and pharmaceutical controls. Nanostructured film composite of sodium montmorillonite clay (Na + MMT) and nickel phthalocyanine (NiTsPc) was selfassembled by layer-by-layer (LbL) technique and applied as electrochemical sensor for DA in the presence of common natural interferents as ascorbic acid (AA) and uric acid (UA). Three different LbL architecture films were investigated: LbL films of clay (PEI/Na + MMT) and phthalocyanine (PEI/NiTsPc) in a bilayer structure with a conventional polyelectrolyte (PEI) and a composite film formed by both materials to verify the synergistic effect in the LbL film in a quadri-layer assembly (PEI/Na + MMT/PEI/NiTsPc). Structural characterization indicated molecular level interactions between the layers forming the LbL films. The ITO/(PEI/Na + MMT/PEI/NiTsPc) 10 electrode exhibited a LOD of 1.0 mol L −1 and linear range 5-150 mol L −1 .

show abstract

Section: Introductionmentioning

confidence: 99%

Layer-by-layer composite film of nickel phthalocyanine and montmorillonite clay for synergistic effect on electrochemical detection of dopamine

Lucena

Miyazaki

Shimizu

et al. 2018

Applied Surface Science

View full text Add to dashboard Cite

show abstract

“…7a. In literature, various types of graphene and its nanocomposite modified GCEs have shown distinct anodic peak for AA oxidation, usually at 0.05 V. [59][60][61][62] But, in the present study there was no oxidation peak, instead it showed an increasing current format in the form of a hump centered at 0.1 V. Similarly, CVs for increasing concentrations of UA neither resulted in any peak nor Determination of DA in the presence of AA and UA.-The non interference of AA and UA, in DA determination has been presented in Fig. 8.…”

Section: Resultsmentioning

confidence: 99%

Ultra-Selective Dopamine Detection in an Excess of Ascorbic Acid and Uric Acid Using Pristine Palladium Nanoparticles Decorated Graphene Modified Glassy Carbon Electrode

Kumar

Siddhardha

Nived

et al. 2015

J. Electrochem. Soc.

View full text Add to dashboard Cite

In the present work, we report the electrochemical detection of dopamine (DA) by means of cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CA) in the presence of excess ascorbic acid (AA) and uric acid (UA) using pristine palladium nanoparticles decorated graphene modified glassy carbon electrode (G/PdNPs-GCE). G/PdNPs nanocomposite was synthesized by preparing pristine PdNPs from its precursor palladium acetylacetonate, with morpholineborane as the reducing agent and subsequently assembled them on graphene nanosheets. The nanocomposite was characterized by field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDX), UV-Vis spectrophotometry and Fourier transform infrared spectroscopy (FTIR). CV, DPV and CA determination of DA showed distinct increase in the current with increasing concentration and a wide range of linearity. The catalytic material exhibited ultra selective detection of dopamine with a peak to peak separation of 90 and 149 mV for AA-DA and DA-UA oxidation respectively. The reduced overpotential for simultaneous oxidation of DA, AA and UA in DPV and CV is also a remarkable feature of the catalytic material. More importantly, the modified electrode exhibited clear and distinct peak for DA in CV and DPV even in the presence of 300 and 450 times excess of AA and UA respectively.DA, an electroactive excitatory catecholamine neurotransmitter coexists with AA and UA in the extracellular fluids of central nervous system (CNS) of mammals. 1 It is produced from its precursor L-Dopa by means of decarboxylation, in the adrenal glands and some parts of the brain. 2 It plays an important role in the brain-body coordination, renal, cardiovascular and hormonal systems. 3 Abnormal levels of DA in humans, often leads to serious disorders like Schizophrenia, Parkinson's disease, ADHD and Huntington's disease. 4 It is also involved in drug addiction affecting the dopaminergic pathways. AA on the other hand plays an important role as an antioxidant and is the vital supplement of our diet. Its deficiency causes scurvy and is essentially involved in functions related to immune system and connective tissues. 5 UA is also a natural antioxidant and primary purine metabolite. Its deficiency is associated with hyperuricemia, Parkinson's disease and gout. 6 Many analytical methods such as spectrophotometry, 7 HPLC, 8 ion chromatography 9 and electrochemical methods 10-12 have been developed hitherto, for the determination of DA. Among them, electrochemical detection has been gaining a lot of importance on account of its low cost, rapid response, ease of operation, miniaturization and low sample volume requirements. 13 Additionally, other techniques are expensive, require extensive sample preparation and specialized equipment. The caveat however is that AA and UA coexisting with DA exhibit overlapping oxidation potentials and pronounced fouling on conventional solid electrodes, complicating the electrochemical detection of DA. 14 Moreover, AA is 100-1000 ...

show abstract

“…Many of the analytical methods used for determination of AA such as fl uorimetry, chromatography, iodometric titration, enzymatic methods, spectroscopy and electrochemistry 20-23 . Due to high sensitivity, selectivity, precision, accuracy, wide linear range and low-cost instrumentation and time, electrochemical methods are currently of much interest for AA determination especially; differential pulse voltammetry (DPV) is a practical electrochemical analytical technique that offers quick response, low detection limit and simple use 24, 25 . This study aims to investigate (i) the electro-synthesis of poly(aniline-co-para-aminophenol) on composite graphite electrode, (ii) electro-catalytic oxidation of AA and its measurement on modifi ed electrodes using DPV method and (iii) the charge transfer resistance (Rct) of modifi ed electrode on AA by electrochemical impedance spectroscopy (EIS).…”

Section: 13mentioning

confidence: 99%

Determination of ascorbic acid using differential pulse voltammetry method on aniline-co-para–aminophenol modified electrode

Parsa

Tajik

2017

Polish Journal of Chemical Technology

View full text Add to dashboard Cite

The electro-synthesis of poly(aniline-co-para-aminophenol) on graphite electrode was examined using cyclic voltammetry (CV) over the potential window of −0.2 V to 1 V in phosphoric acid medium, which was comprised of potassium chloride and para-Toluene sulfonic acid (pTSA) as electrolyte support. Fourier transform infrared (FTIR) spectroscopy was employed to identify the electro-synthesized copolymer while impedance techniques were used to determine charge transfer resistance (Rct) in modifi ed and unmodifi ed electrodes. After this, the electro-catalytic effect of the modifi ed electrode on ascorbic acid was examined using differential pulse voltammetry (DPV) and a very strong response was observed. A negative shift of about 0.33 V was found in the peak anodic potentials for ascorbic acid. Measurement using DPV indicated a proper response by the electrode to a wide range of ascorbic acid concentrations, from 0.0001 to 0.0004 M. The peak anodic currents for increased concentrations showed a proper linear range.

show abstract

Selective determination of dopamine in the presence of uric acid and ascorbic acid by N,N′-bis(indole-3-carboxaldimine)-1,2-diaminocyclohexane thin film modified glassy carbon electrode by differential pulse voltammetry

Cited by 30 publications

References 54 publications

Layer-by-layer composite film of nickel phthalocyanine and montmorillonite clay for synergistic effect on electrochemical detection of dopamine

Layer-by-layer composite film of nickel phthalocyanine and montmorillonite clay for synergistic effect on electrochemical detection of dopamine

Ultra-Selective Dopamine Detection in an Excess of Ascorbic Acid and Uric Acid Using Pristine Palladium Nanoparticles Decorated Graphene Modified Glassy Carbon Electrode

Determination of ascorbic acid using differential pulse voltammetry method on aniline-co-para–aminophenol modified electrode

Contact Info

Product

Resources

About