Selective C2 and C3 phosphorylmethylation of indoles with a phosphorylmethyl dibenzothiophenium reagent

Abstract

A novel electrophilic phosphorylmethylating reagent, S-([diethoxyphosphoryl]methyl) dibenzothiophenium salt, has been successfully synthesized with readily available starting materials. This reagent is air- and moisture-tolerant and bench-stable. Interestingly, the reagent exhibited excellent...