Selective BODIPY® based fluorescent chemosensor for imaging Pb2+ ion in living cells

Baruah, Mukulesh; Huntimer, Eric; Ahmed, Mahmoud S.; Hoppe, Adam D.; Halaweish, Fathi T.

doi:10.1016/j.tetlet.2012.05.092

Cited by 6 publications

(1 citation statement)

References 10 publications

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“…Most importantly proposed receptor design could penetrate living membrane without harming cells, and was further utilized for detection of Pb 2+ during live cell imaging. (Figure 3) [42,43]. Receptor 3 offered selective recognition of Pb 2+ under physiological conditions (20 mM HEPES buffer).…”

Section: Abiotic Fluorescent Receptorsmentioning

confidence: 99%

Abiotic Fluorescent Receptors for Detection of Pb2+ in Aqueous Media as well as Living Cells: Mechanistic and Sensing Aspects

Kaloo¹,

Bhat²,

Shalla³

2017

Biomark J

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Substantial utility of lead in numerous industries (storage, batteries, gasoline, cable manufacture, paint and ammunition), has resulted in recurring of environmental contamination. Lead being one of the highly abundant elements in nature, ranks third among the list of toxic substances. Owing to its ever-increasing demand and allied toxicity (memory loss, irritability, anemia, muscle paralysis, and mental retardation), development of novel synthetic receptors suitable to track Pb 2+ in vitro as well as in vivo has been an exciting area of research in the past few decades. In this review, emphasis has been diverted to summarize and briefly discuss major contributions made towards development of fluorescent abiotic receptors capable of sensing ionic lead (Pb 2+ ) under aqueous environments as well as in living cells.

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Section: Abiotic Fluorescent Receptorsmentioning

confidence: 99%

Abiotic Fluorescent Receptors for Detection of Pb2+ in Aqueous Media as well as Living Cells: Mechanistic and Sensing Aspects

Kaloo¹,

Bhat²,

Shalla³

2017

Biomark J

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Straightforward Synthetic Protocol for the Introduction of Stabilized C Nucleophiles in the BODIPY Core for Advanced Sensing and Photonic Applications

Gutiérrez-Ramos

Bañuelos

Arbeloa

et al. 2014

Chemistry A European J

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A straightforward synthetic protocol to directly incorporate stabilized 1,3‐dicarbonyl C nucleophiles to the meso position of BODIPY (4,4‐difluoro‐4‐bora‐3a,4a‐diaza‐s‐indacene) is reported. Soft nucleophiles generated by deprotonation of 1,3‐dicarbonyl derivatives smoothly displace the 8‐methylthio group from 8‐(methylthio)BODIPY analogues in the presence of CuI thiophenecarboxylate in stoichiometric amounts at room temperature. Seven highly fluorescent new derivatives are prepared with varying yields (20–92 %) in short reaction times (5–30 min). The excellent photophysical properties of the new dyes allow focusing on applications never analyzed before for BODIPYs substituted with stabilized C nucleophiles such as pH sensors and lasers in liquid and solid state, highlighting the relevance of the synthetic protocol described in the present work. The attainment of these dyes, with strong UV absorption and highly efficient and stable laser emission in the green spectral region, concerns to one of the greatest challenges in the ongoing development of advanced photonic materials with relevant applications. In fact, organic dyes with emission in the green are the only ones that allow, by frequency‐doubling processes, the generation of tunable ultraviolet (250‐350 nm) radiation, with ultra‐short pulses.

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Synthesis of fluorescent di-dansyl substituted ethoxy compound: A selective sensor for antimony and thallium metals detection

Qureshi

Ehtisham-ul-Haque

Abbas

et al. 2019

Journal of Materials Research and Technology

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Selective BODIPY® based fluorescent chemosensor for imaging Pb2+ ion in living cells

Cited by 6 publications

References 10 publications

Abiotic Fluorescent Receptors for Detection of Pb2+ in Aqueous Media as well as Living Cells: Mechanistic and Sensing Aspects

Abiotic Fluorescent Receptors for Detection of Pb2+ in Aqueous Media as well as Living Cells: Mechanistic and Sensing Aspects

Straightforward Synthetic Protocol for the Introduction of Stabilized C Nucleophiles in the BODIPY Core for Advanced Sensing and Photonic Applications

Synthesis of fluorescent di-dansyl substituted ethoxy compound: A selective sensor for antimony and thallium metals detection

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