Selective and efficient detection of picric acid among other nitroaromatics by NIR fluorescent cyanine chemosensors

CF3 H-bonding locked aromatic stacking of picric acid with mechanofluorochromic fluorophores: highly selective reusable sensor and rewritable fluorescence platform

“…4-(9H-Carbazol-9yl)benzaldehyde and 4-(diphenylamino)benzaldehyde were synthesized following a reported procedure. 50 General procedure for synthesizing Cz-4-CF 3 , Cz-4-CH 3 , Cz-3-CF 3 , TPA-4-CF 3 and TPA-3-CF 3 4-(9H-Carbazol-9-yl)benzaldehyde/4-(diphenylamino)benzaldehyde (1.0 equivalent) was dissolved in methanol and stirred at room temperature. To this solution, CF 3 /CH 3 substituted phenylacetonitrile (1.3 equivalents) and sodium methoxide (2 equivalents) were added, and the reaction mixture was stirred at room temperature for 2 h. Finally, the reaction mixture was cooled to room temperature, and the product was filtered and washed with cold methanol.…”

“…4-(9 H -Carbazol-9-yl)benzaldehyde and 4-(diphenylamino)benzaldehyde were synthesized following a reported procedure. 50…”

“…The fabrication of a selective and sensitive fluorescent sensor for picric acid (PA) has received considerable attention recently, owing to its widespread usage in lethal weapons, fireworks, dyes and ointments. [43][44][45][46][47][48][49][50] Exposure to PA in skin, liver, kidneys and the respiratory system in humans and animals causes detrimental effects. [51][52][53][54] The high acidity and water solubility of PA increases the risk of water and soil contamination.…”

Stimuli-Responsive Polymeric Nanocarriers for Drug Delivery, Imaging, and Theragnosis

“…Near-infrared (NIR) is a strategy that used by optical imaging systems because of the extremely low absorption of tissues in the wavelength of 700–1000 nm [ 223 ]. Small organic molecules with superior optical properties (high molar absorption, good photostability, and high fluorescent emissions in the NIR area) are fluorescent NIR probes such as cyanine compounds [ 224 ]. Such molecules, indeed, can be quickly degraded in aqueous media and in physiological environments are distinguished by a limited circulation time.…”

Chemoselective Detection of 2,4,6‐trinitrophenol by Ground State Adduct Formation via Protonation of Quinoline Moiety of Non‐heme Ligands with Structural Evidence

“…[12] A hemicyanine dye bearing conjugated 4-(dimethylamino)benzaldehyde based fluorophores are known for its valuable property of sensing TNP. [13] A large number of quinoline based compounds are also proven to be effective as fluorophores in TNP detection. [14] Britovsek et al in their work have investigated the effect of ligand topology on the field strength of non-heme iron(II) catalyzed reactions by using different bis(quinolyl) based tetradentate ligands (Scheme S1).…”