2019
DOI: 10.1016/j.jim.2019.112647
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Selection of potential cytokeratin-18 monoclonal antibodies following IGH repertoire evaluation in mice

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“…In soil microbial sequencing, a bacterial genome’s 16S rRNA gene fragment is first amplified and sequenced, followed by studying the colony type and microorganism structure through bioinformatic analyses ( 3 , 5 , 7 , 8 ). Recently, with the development of research and technology, second-generation high-throughput sequencing (NGS) technology has emerged, which is a modification of the traditional Sanger sequencing ( 9 11 ). This technology can sequence many microbial DNA molecules in the V4 region of a soil sample in parallel in a single run and has a substantial quantitative capability, where the number of times a DNA sample is sequenced directly reflects the DNA abundance of that sample.…”
Section: Introductionmentioning
confidence: 99%
“…In soil microbial sequencing, a bacterial genome’s 16S rRNA gene fragment is first amplified and sequenced, followed by studying the colony type and microorganism structure through bioinformatic analyses ( 3 , 5 , 7 , 8 ). Recently, with the development of research and technology, second-generation high-throughput sequencing (NGS) technology has emerged, which is a modification of the traditional Sanger sequencing ( 9 11 ). This technology can sequence many microbial DNA molecules in the V4 region of a soil sample in parallel in a single run and has a substantial quantitative capability, where the number of times a DNA sample is sequenced directly reflects the DNA abundance of that sample.…”
Section: Introductionmentioning
confidence: 99%