“…✉ email: asuh@tulane.edu Depending on severity of penetration, microsurgical repair and systemic antibiotics may be indicated. The ISS is equipped with a comprehensive array of medications, comparable to those used in terrestrial management of corneal perforations, capable of minimizing the risk of infection and offering therapeutic relief [9,10]. Topical anaesthetics (e.g., tetracaine (0.5%, 15 mL)), cycloplegic drops (e.g., cyclopentolate (Cyclogyl) 2%, 15 mL; tropicamide (Mydriacyl) 1%, 15 mL), and anti-inflammatory and analgesic agents (e.g., ketorolac (Toradol) 30 mg/mL, 2 mL; acetaminophen (Tylenol) 325 mg; Aspirin 325 mg; Ibuprofen (Motrin) 400 mg) may provide relief during the painful ocular injury.…”