Selection of Donors for Adult Living-Donor Liver Donation: Results of the Assessment of the First 205 Donor Candidates

Erim, Yeşim; Beckmann, Mingo; Valentin‐Gamazo, Camino; Malagó, Massimo; Frilling, Andrea; Schlaak, Joerg F.; Gerken, Guido; Broelsch, Christoph E.; Senf, Wolfgang

doi:10.1176/appi.psy.49.2.143

Cited by 31 publications

(37 citation statements)

References 30 publications

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“…Meanwhile, they were unable to grasp more information given to them about the donation procedure and to communicate their decision with the transplant team. This result was similar to that of Erim et al [32] who found that depression was less in highly educated group of donors, as they lived within a wellestablished social context and were more confident that they could handle the physical, mental, and financial burdens of organ transplantation. Being a student and working in managerial job were found to be statistically significant to depression by the linear regression analysis.…”

Section: Risk Factors Associated With Depressive Symptoms In Donors Asupporting

confidence: 89%

Factors correlated with the emergence of depressive symptoms in Egyptian donors after living donor liver transplantation

El-Meteini¹,

Hamed²,

Awaad³

et al. 2014

Middle East Current Psychiatry

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Section: Risk Factors Associated With Depressive Symptoms In Donors Asupporting

confidence: 89%

Factors correlated with the emergence of depressive symptoms in Egyptian donors after living donor liver transplantation

El-Meteini¹,

Hamed²,

Awaad³

et al. 2014

Middle East Current Psychiatry

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“…In particular, survey questionnaires using the term "coercion" often fail to define it (23). Nonetheless, LKD and LLD candidates' reports of hesitancy, reluctance (76), anxiety (60,61), fear (77), and insecurity about the decision to donate (67) suggest that LDs may feel undue pressure. On the other hand, the fact that donors do withdraw from evaluation indicates that they are capable of expressing a voluntary, autonomous decision not to donate (78).…”

Section: Voluntarinessmentioning

confidence: 99%

Informed Consent for Living Donation: A Review of Key Empirical Studies, Ethical Challenges and Future Research

Gordon

2012

American Journal of Transplantation

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Given the organ scarcity, live organ donation is increasingly considered a viable alternative for kidney and liver transplantation. Yet living donation challenges the ethical principle of nonmaleficence by subjecting healthy individuals to medical, psychosocial and unknown risks. Therefore, transplant providers, policymakers and donors are committed to ensuring that prospective donors provide adequate informed consent to undergo the procedure. Informed consent for living donation is ethically required as a means of demonstrating respect for donor's autonomy and protecting their safety. However, all elements of informed consent are fraught with difficulties due to the unique nature of the donation process and outcome. This paper reviews empirical research on informed consent for live kidney donors (LKD) and live liver donors (LLD) for both adult and pediatric recipients. As this review shows, studies that empirically assessed the quality of informed consent elements reveal considerable variability and deficiencies across the informed consent process, suggesting the need for improvement. This review highlights challenges to each element of consent for both LKDs and LLDs, and situates trends within broader policy contexts, ethical debates and avenues for future innovative research.

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“…Existing studies suggest that liver donors enjoy a similar, if not better HRQOL compared with the general population, and that the vast majority of donors would go through the process again (10)(11)(12)(13)(14). However, in order to develop effective guidelines for donor selection and enhance donor quality of care, there is a need for research that not only describes donor HRQOL postdonation, but also identifies risk factors for poor HRQOL outcomes (15). …”

Section: The Living Donor Partial Hepatectomy Provides No Physical Bementioning

confidence: 99%

Adult Right-Lobe Living Liver Donors: Quality of Life, Attitudes and Predictors of Donor Outcomes

DuBay

Holtzman

Adcock

et al. 2009

American Journal of Transplantation

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To refine selection criteria for adult living liver donors and improve donor quality of care, risk factors for poor postdonation health-related quality of life (HRQOL) must be identified. This cross-sectional study examined donors who underwent a right hepatectomy at the University of Toronto between 2000 and 2007 (n = 143), and investigated predictors of (1) physical and mental health postdonation, as well as (2) willingness to participate in the donor process again. Participants completed a standardized HRQOL measure (SF-36) and measures of the pre-and postdonation process. Donor scores on the SF-36 physical and mental health indices were equivalent to, or greater than, population norms. Greater predonation concerns, a psychiatric diagnosis and a graduate degree were associated with lower mental health postdonation whereas older donors reported better mental health. The majority of donors (80%) stated they would donate again but those who perceived that their recipient engaged in risky health behaviors were more hesitant. Prospective donors with risk factors for lower postdonation satisfaction and mental health may require more extensive predonation counseling and postdonation psychosocial follow-up. Risk factors identified in this study should be prospectively evaluated in future research. participate (n = 204). Procedures used by our center to determine donor suitability for right hepatectomy have been reported elsewhere (1). Eleven donors who had been either lost to follow-up (n = 9) or who informed our program that they were doing well and no longer required follow-up (n = 2) were not contacted. Study designThis is a cross-sectional study in which donors who were at least 3 months postdonation were mailed a package of materials that contained a cover letter explaining the study objectives, a consent form and a written questionnaire. Only those measures that were analyzed in this report will be described here. Postdonation questionnaireLiving liver donors completed a one-time comprehensive questionnaire assessing demographics (sex, age, marital status, ethnicity, education, income and employment

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Selection of Donors for Adult Living-Donor Liver Donation: Results of the Assessment of the First 205 Donor Candidates

Cited by 31 publications

References 30 publications

Factors correlated with the emergence of depressive symptoms in Egyptian donors after living donor liver transplantation

Factors correlated with the emergence of depressive symptoms in Egyptian donors after living donor liver transplantation

Informed Consent for Living Donation: A Review of Key Empirical Studies, Ethical Challenges and Future Research

Adult Right-Lobe Living Liver Donors: Quality of Life, Attitudes and Predictors of Donor Outcomes

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