Selection of collagen IV fragments forming the outer sphere of the native protein: Assessment of biological activity for regenerative medicine
Angelika Becht,
Justyna Frączyk,
Joanna Waśko
et al.
Abstract:The aim of this research was to select the fragments that make up the outer layer of the collagen IV (COL4A6) protein and to assess their potential usefulness for regenerative medicine. It was expected that because protein–protein interactions take place via contact between external domains, the set of peptides forming the outer sphere of collagen IV will determine its interaction with other proteins. Cellulose‐immobilized protein fragment libraries treated with polyclonal anti‐collagen IV antibodies were used… Show more
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