Selection for surgery and survival of synchronous colorectal liver metastases; a nationwide study

Norén, Agneta; Eriksson, Henrik; Olsson, Louise

doi:10.1016/j.ejca.2015.10.055

Cited by 76 publications

(82 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the present study, 37.5% of patients were referred with seemingly large variations between hospitals, although statistically nonsignificant. In a Swedish nationwide study by Norén et al, the resection rates of synchronous liver metastases varied considerably between different regions in Sweden and were lower in regions outside of the Stockholm area . The present study further showed that predictors associated with referral to liver MDT were age, ASA score and number of liver metastases and number of liver metastases.…”

Section: Discussionsupporting

confidence: 66%

The Impact of a Hepatobiliary Multidisciplinary Team Assessment in Patients with Colorectal Cancer Liver Metastases: A Population-Based Study

Engstrand

Kartalis

Strömberg³

et al. 2017

The Oncologist

View full text Add to dashboard Cite

Patients with liver metastatic colorectal cancer who are assessed at a hepatobiliary multidisciplinary meeting achieve higher resection rates and improved survival. Unfortunately, patients who may benefit from resection are not always properly referred. In this study, the potential improved resection rate was assessed by re-evaluating all patients with liver metastases from a population-based cohort, including patients with extrahepatic metastases and accounting for comorbidity and patients' own preferences towards treatment. An additional 12.9% of the patients were found to be potentially resectable. The results highlight the importance of all patients being evaluated in the setting of a hepatobiliary multidisciplinary meeting.

show abstract

Section: Discussionsupporting

confidence: 66%

The Impact of a Hepatobiliary Multidisciplinary Team Assessment in Patients with Colorectal Cancer Liver Metastases: A Population-Based Study

Engstrand

Kartalis

Strömberg³

et al. 2017

The Oncologist

View full text Add to dashboard Cite

show abstract

“…In the present study, a cumulative resection rate of 20·0 per cent was calculated for synchronous and metachronous CLM combined. A lower resection rate (6·8 per cent) was observed in patients with synchronous disease compared with rates found by van der Geest and co‐workers and Norèn et al …”

Section: Discussionmentioning

confidence: 45%

“…In 2015, van der Geest and colleagues presented data from a Dutch registry comprising patients with synchronous CLM (1996–2011), of whom 18 per cent underwent liver resection during the last part of the study interval. Analysis of data from the Swedish Cancer Registry for synchronous CLM showed a 17·8 per cent resection rate. Limitations of the last two studies were the lack of data on patients with metachronous disease.…”

Section: Discussionmentioning

confidence: 99%

Population-based study on resection rates and survival in patients with colorectal liver metastasis in Norway

Angelsen

Horn

Sørbye

et al. 2017

British Journal of Surgery

View full text Add to dashboard Cite

show abstract

“…Socioeconomic factors may be relevant here, but a prospective study in a primary R0 cohort would be needed to see whether there is a sex difference related to more aggressive spread 19 . Socioeconomic factors may be relevant here, but a prospective study in a primary R0 cohort would be needed to see whether there is a sex difference related to more aggressive spread 19 .…”

Section: Discussionmentioning

confidence: 99%

Influence of primary tumour and patient factors on survival in patients undergoing curative resection and treatment for liver metastases from colorectal cancer

et al. 2020

View full text Add to dashboard Cite

Background: Resection of the primary tumour is a prerequisite for cure in patients with colorectal cancer, but hepatic metastasectomy has been used increasingly with curative intent. This national registry study examined prognostic factors for radically treated primary tumours, including the subgroup of patients undergoing liver metastasectomy. Methods: Patients who had radical resection of primary colorectal cancer in 2009-2013 were identified in a population-based Swedish colorectal registry and cross-checked in a registry of liver tumours. Data on primary tumour and patient characteristics were extracted and prognostic impact was analysed.Results: Radical resection was registered in 20 853 patients; in 38⋅7 per cent of those registered with liver metastases, surgery or ablation was performed. The age-standardized relative 5-year survival rate after radical resection of colorectal cancer was 80⋅9 (95 per cent c.i. 80⋅2 to 81⋅6) per cent, and the rate after surgery for colorectal liver metastases was 49⋅6 (46⋅0 to 53⋅2) per cent. Multivariable analysis identified lymph node status, multiple sites of metastasis, high ASA grade and postoperative complications after resection of the primary tumour as strong risk factors after primary resection and following subsequent liver resection or ablation. Age, sex and primary tumour location had no prognostic impact on mortality after liver resection.Conclusion: Lymph node status and complications have a negative impact on outcome after both primary resection and liver surgery. Older age and female sex were underrepresented in the liver surgical cohort, but these factors did not influence prognosis significantly.

show abstract

Selection for surgery and survival of synchronous colorectal liver metastases; a nationwide study

Cited by 76 publications

References 21 publications

The Impact of a Hepatobiliary Multidisciplinary Team Assessment in Patients with Colorectal Cancer Liver Metastases: A Population-Based Study

The Impact of a Hepatobiliary Multidisciplinary Team Assessment in Patients with Colorectal Cancer Liver Metastases: A Population-Based Study

Population-based study on resection rates and survival in patients with colorectal liver metastasis in Norway

Influence of primary tumour and patient factors on survival in patients undergoing curative resection and treatment for liver metastases from colorectal cancer

Contact Info

Product

Resources

About