Selection for high and low level of 5α‐androst‐16‐en‐3‐one in boars

Willeke, H.; Claus, R.; Müller, Elisabeth; Pirchner, F.; Karg, H.

doi:10.1111/j.1439-0388.1987.tb00110.x

Cited by 25 publications

(7 citation statements)

References 19 publications

(5 reference statements)

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“…Thus the low end extremes could not be selected. W illeke et al (1987) found similar results selecting for high and low levels of 5α‐androstenone. These researchers also showed asymmetric response in the high and low line that was mainly caused by the very small selection differential in the low line and probably by the approach of the concentration to the biological limit.…”

Section: Resultssupporting

confidence: 55%

“…The realized heritability in the high line was very close to that estimated from son‐sire regression, whereas that in the low line was somewhat lower. These estimates were considerably lower than the estimates of B onneau and S ellier (1986) and W illeke et al (1987) for 5α‐androstenone (.61 and .56, respectively), but comfortably within the range of estimates reported by T oelle et al (1984) and E den et al (1978) for testicular traits; J onsson and A ndresen (1979) for 5α‐androstenone and L ubritz et al (1991) for testosterone.…”

Section: Resultssupporting

confidence: 46%

“…In pigs, age at first farrowing and NBA were favorably correlated with 140‐d testes measures (T oelle and R obison 1985). W illeke et al (1987) observed that boars selected for high levels of 5α‐androstenone had a significantly higher level of conjugated oestrogen than males of the low line. W illeke also observed that gilts of the high line exhibited first estrus 14 d earlier than gilts of the low line.…”

Section: Resultsmentioning

confidence: 92%

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Realized heritability estimates in boars divergently selected for testosterone levels^1,²

Robison

Lubritz

Johnson

1994

J Animal Breeding Genetics

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Data were collected from 1982 through 1992 from 100 sires and 891 Duroc boars. Testosterone production was measured from peripheral blood samples before (PRE) and after (POST) GnRH challenge. Additionally, data were collected on testes volume at 168 d (TVOL), days to 104 kg (DAYS104), number born alive (NBA) and backfat adjusted to 104 kg body weight (FAT). Realized heritabilities were estimated from the regression of response on cumulative selection differentials. Heritabilities for POST were .15 ± .18 and .24 ± .08 in the low and high lines, respectively. This compares with the estimate of .26 ± .21 from son-sire regressions. The regression of other traits on cumulative selection differentials can be viewed as realized correlated responses to selection. After 10 generations, the high line was approximately three times greater than the low line for both PRE and POST levels of testosterone. Although not significant, high line pigs required fewer days to reach 104 kg, had more backfat and larger testes than low line pigs. Litter size was significantly larger for high line than for low line. ZUSAMMENFASSUNG: Realisierte Heritabilitätsschätzungen von Divergenz für Testosteronspiegel selektierten Ebern Die Daten stammen aus dem Zeitraum 1982-1992 von 891 Duroc Ebern aus 100 Vatertieren. Testosteronproduktion wurde von peripheren Blutproben vor (PRE) und nach (POST) GnRH-Gaben gemessen. Zusätzlich wurden Angaben über Hodenvolumen am Tag 168 (TVOL), Zeitraum bis 104 kg Lebendgewicht (DAYS104), Zahl lebend geborener (NBA) und auf 104 kg Körpergewicht korrigierte Rückenspeckdicke (FAT) erhoben. Realisierte Heritabilitätswerte wurden aus der Regression von Selektionserfolg auf kumulative Selektionsdifferenzen geschätzt. Heritabilität für POST waren 0,15 ± 0,18 und 0,24 ± 0,08 in der Minus- und in der Pluslinie. Aus Sohn-Vater-Regressionen ergab sich 0,26 ± 0,21. Die Regression anderer Eigenschaften auf kumulative Selektionsdifferenzen können als realisierte korrelierte Selektionserfolge betrachtet werden. Nach 10 Generationen hatte die Pluslinie etwa dreimal höhere PRE- und POST-Spiegel von Testosteron als die Minuslinie. Obwohl nicht signifikant, brauchten Schweine der Pluslinie weniger Tage bis 104 kg, waren fetter und hatten größere Hoden als Schweine der Minuslinie. Die Wurfgröße der Pluslinie war höher als in der niedrigen Linie.

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Section: Resultssupporting

confidence: 55%

Section: Resultssupporting

confidence: 46%

Section: Resultsmentioning

confidence: 92%

See 1 more Smart Citation

Realized heritability estimates in boars divergently selected for testosterone levels^1,²

Robison

Lubritz

Johnson

1994

J Animal Breeding Genetics

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“…Strong genetic correlations between AND and other sex steroids, like for example, testosterone have been reported by, for example, Willeke et al (1987) and Grindflek et al (2011). Moreover, the level of AND has been found to be strongly correlated with testes size (Sellier and Bonneau, 1988) and size of the bulbo-urethral gland (Sellier et al, 2000).…”

Section: Expected Change In Average Amount Of Boar Taintmentioning

confidence: 93%

Efficiency of different selection strategies against boar taint in pigs

Haberland

Luther

Höfer

et al. 2014

Animal

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The breeding scheme of a Swiss sire line was modeled to compare different target traits and information sources for selection against boar taint. The impact of selection against boar taint on production traits was assessed for different economic weights of boar taint compounds. Genetic gain and breeding costs were evaluated using ZPlan+, a software based on selection index theory, gene flow method and economic modeling. Scenario I reflected the currently practiced breeding strategy as a reference scenario without selection against boar taint. Scenario II incorporated selection against the chemical compounds of boar taint, androstenone (AND), skatole (SKA) and indole (IND) with economic weights of -2.74, -1.69 and -0.99 Euro per unit of the log transformed trait, respectively. As information sources, biopsy-based performance testing of live boars (BPT) was compared with genomic selection (GS) and a combination of both. Scenario III included selection against the subjectively assessed human nose score (HNS) of boar taint. Information sources were either station testing of full and half sibs of the selection candidate or GS against HNS of boar taint compounds. In scenario I, annual genetic gain of log-transformed AND (SKA; IND) was 0.06 (0.09; 0.02) Euro, which was because of favorable genetic correlations with lean meat percentage and meat surface. In scenario II, genetic gain increased to 0.28 (0.20; 0.09) Euro per year when conducting BPT. Compared with BPT, genetic gain was smaller with GS. A combination of BPT and GS only marginally increased annual genetic gain, whereas variable costs per selection candidate augmented from 230 Euro (BPT) to 330 Euro (GS) or 380 Euro (both). The potential of GS was found to be higher when selecting against HNS, which has a low heritability. Annual genetic gain from GS was higher than from station testing of 4 full sibs and 76 half sibs with one or two measurements. The most effective strategy to reduce HNS was selecting against chemical compounds by conducting BPT. Because of heritabilities higher than 0.45 for AND, SKA and IND and high genetic correlations to HNS, the (correlated) response in units of the trait could be increased by 62% compared with scenario III with GS and even by 79% compared with scenario III, with station testing of siblings with two measurements. Increasing the economic weights of boar taint compounds amplified negative effects on average daily gain, drip loss and intramuscular fat percentage.

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“…Studies have found unfavorable correlations between the androstenone level in fat and reproduction traits (Willeke et al . ; Sellier & Bonneau ; Tajet et al . ; Mathur et al .…”

Section: Snp Association and Effect For Traits Under Study In Three Cmentioning

confidence: 99%

Asian low‐androstenone haplotype on pig chromosome 6 does not unfavorably affect production and reproduction traits

et al. 2014

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European pigs that carry Asian haplotypes of a 1.94-Mbp region on pig chromosome 6 have lower levels of androstenone, one of the two main compounds causing boar taint. The objective of our study was to examine potential pleiotropic effects of the Asian low-androstenone haplotypes. A single nucleotide polymorphism marker, rs81308021, distinguishes the Asian from European haplotypes and was used to investigate possible associations of androstenone with production and reproduction traits. Eight traits were available from three European commercial breeds. For the two sow lines studied, a favorable effect on number of teats was detected for the low-androstenone haplotype. In one of these sow lines, a favorable effect on number of spermatozoa per ejaculation was detected for the low-androstenone haplotype. No unfavorable pleiotropic effects were found, which suggests that selection for low-androstenone haplotypes within the 1.94 Mbp would not unfavorably affect the other eight relevant traits.

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Selection for high and low level of 5α‐androst‐16‐en‐3‐one in boars

Cited by 25 publications

References 19 publications

Realized heritability estimates in boars divergently selected for testosterone levels^1,²

Realized heritability estimates in boars divergently selected for testosterone levels^1,²

Efficiency of different selection strategies against boar taint in pigs

Asian low‐androstenone haplotype on pig chromosome 6 does not unfavorably affect production and reproduction traits

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Selection for high and low level of 5α‐androst‐16‐en‐3‐one in boars

Cited by 25 publications

References 19 publications

Realized heritability estimates in boars divergently selected for testosterone levels1,2

Realized heritability estimates in boars divergently selected for testosterone levels1,2

Efficiency of different selection strategies against boar taint in pigs

Asian low‐androstenone haplotype on pig chromosome 6 does not unfavorably affect production and reproduction traits

Contact Info

Product

Resources

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Realized heritability estimates in boars divergently selected for testosterone levels^1,²

Realized heritability estimates in boars divergently selected for testosterone levels^1,²