Selection and in vitro and in vivo characterization of a Kunitz protease inhibitor domain of protease nexin 2 variant that inhibits factor XIa without inhibiting plasmin

Eltringham-Smith, Louise J.; Bhakta, Varsha; Sheffield, William P.

doi:10.1016/j.jbiotec.2021.02.016

Journal of Biotechnology

2021

DOI: 10.1016/j.jbiotec.2021.02.016

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Selection and in vitro and in vivo characterization of a Kunitz protease inhibitor domain of protease nexin 2 variant that inhibits factor XIa without inhibiting plasmin

Louise J. Eltringham-Smith

Varsha Bhakta

William P. Sheffield

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Cited by 3 publications

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Sun,

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et al. 2024

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Selection and in vitro and in vivo characterization of a Kunitz protease inhibitor domain of protease nexin 2 variant that inhibits factor XIa without inhibiting plasmin

Cited by 3 publications

References 24 publications

Design, expression and biological evaluation of DX-88mut as a novel selective factor XIa inhibitor for antithrombosis

Design, expression and biological evaluation of DX-88mut as a novel selective factor XIa inhibitor for antithrombosis

Evaluation of venom diversity and antivenom quality from the venom of long-term captive vs recently wild captured Pseudocerastes persicus snake: An In vitro and In vivo study

Proteomic Markers and Early Prediction of Alzheimer’s Disease

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