Selected Mineral Intakes of Adult African-Americans in the Washington, DC Area

Ellis, Rebecca; Morris, E. Matthew; Hill, A. David; Smith, James C.; Harland, Barbara F.

doi:10.1006/jfca.1997.0545

Cited by 6 publications

(5 citation statements)

References 9 publications

(5 reference statements)

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“…In African-American adults in the US, the median of the daily phytate intake was 538 mg, with strong differences for females (512 mg) and males (608 mg) [131].…”

Section: North and Central Americamentioning

confidence: 99%

Phytate in foods and significance for humans: Food sources, intake, processing, bioavailability, protective role and analysis

Schlemmer¹,

Frølich

Prieto

et al. 2009

Molecular Nutrition Food Res

727

604

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The article gives an overview of phytic acid in food and of its significance for human nutrition. It summarises phytate sources in foods and discusses problems of phytic acid/phytate contents of food tables. Data on phytic acid intake are evaluated and daily phytic acid intake depending on food habits is assessed. Degradation of phytate during gastro-intestinal passage is summarised, the mechanism of phytate interacting with minerals and trace elements in the gastro-intestinal chyme described and the pathway of inositol phosphate hydrolysis in the gut presented. The present knowledge of phytate absorption is summarised and discussed. Effects of phytate on mineral and trace element bioavailability are reported and phytate degradation during processing and storage is described. Beneficial activities of dietary phytate such as its effects on calcification and kidney stone formation and on lowering blood glucose and lipids are reported. The antioxidative property of phytic acid and its potentional anticancerogenic activities are briefly surveyed. Development of the analysis of phytic acid and other inositol phosphates is described, problems of inositol phosphate determination and detection discussed and the need for standardisation of phytic acid analysis in foods argued.

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“…In African-American adults in the US, the median of the daily phytate intake was 538 mg, with strong differences for females (512 mg) and males (608 mg) [131].…”

Section: North and Central Americamentioning

confidence: 99%

Phytate in foods and significance for humans: Food sources, intake, processing, bioavailability, protective role and analysis

Schlemmer¹,

Frølich

Prieto

et al. 2009

Molecular Nutrition Food Res

727

604

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“…In Europe, InsP6 is far below daily doses; for instance, a recent study in Italy indicated a very lower range of phytic acid intake compared to the supposed daily dosage (from 219 to 293 mg/daily) [14,47]. In the USA and Canada, the average phytic acid intake is 538 mg/daily in adults, with relevant differences between males and females (608 mg vs. 512 mg/daily, respectively) [48], and 170-390 mg/daily in children [49]. On the contrary, in adult Asian immigrants to Canada consuming a vegetarian diet, the mean daily InsP6 intake increased [50].…”

Section: Inositol Depletion Induced By Reduced Nutritional Availabilitymentioning

confidence: 99%

Inositols Depletion and Resistance: Principal Mechanisms and Therapeutic Strategies

Lepore¹,

Lauretta

Bianchini

et al. 2021

IJMS

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Inositols are natural molecules involved in several biochemical and metabolic functions in different organs and tissues. The term “inositols” refers to five natural stereoisomers, among which myo-Inositol (myo-Ins) is the most abundant one. Several mechanisms contribute to regulate cellular and tissue homeostasis of myo-Ins levels, including its endogenous synthesis and catabolism, transmembrane transport, intestinal adsorption and renal excretion. Alterations in these mechanisms can lead to a reduction of inositols levels, exposing patient to several pathological conditions, such as Polycystic Ovary Syndrome (PCOS), hypothyroidism, hormonal and metabolic imbalances, like weight gain, hyperinsulinemia, dyslipidemia, and metabolic syndrome. Indeed, myo-Ins is involved in different physiological processes as a key player in signal pathways, including reproductive, hormonal, and metabolic modulation. Genetic mutations in genes codifying for proteins of myo-Ins synthesis and transport, competitive processes with structurally similar molecules, and the administration of specific drugs that cause a central depletion of myo-Ins as a therapeutic outcome, can lead to a reduction of inositols levels. A deeper knowledge of the main mechanisms involved in cellular inositols depletion may add new insights for developing tailored therapeutic approaches and shaping the dosages and the route of administration, with the aim to develop efficacious and safe approaches counteracting inositols depletion-induced pathological events.

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“…A significant lower InsP6 intake has indeed recorded especially in younger people. Both US and Canadian children showed a mean daily phytate intake ranging from 170 to 390 mg/day [ 73 , 74 ], while in adults the median intake is significantly higher, averaging 538 mg/day, even if relevant differences have been found between Males and Females (608 mg vs. 512 mg/day, respectively) [ 75 ]. These data should be put in parallel with those obtained in adult Asian immigrants to Canada, consuming mostly a vegetarian diet, in which mean daily InsP6 intake steadily increases (1487 ± 791 mg/day) [ 76 ].…”

Section: Inositol Deficiencymentioning

confidence: 99%

Nutritional and Acquired Deficiencies in Inositol Bioavailability. Correlations with Metabolic Disorders

Dinicola

Minini

Unfer³

et al. 2017

IJMS

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Communities eating a western-like diet, rich in fat, sugar and significantly deprived of fibers, share a relevant increased risk of both metabolic and cancerous diseases. Even more remarkable is that a low-fiber diet lacks some key components—as phytates and inositols—for which a mechanistic link has been clearly established in the pathogenesis of both cancer and metabolic illness. Reduced bioavailability of inositol in living organisms could arise from reduced food supply or from metabolism deregulation. Inositol deregulation has been found in a number of conditions mechanistically and epidemiologically associated to high-glucose diets or altered glucose metabolism. Indeed, high glucose levels hinder inositol availability by increasing its degradation and by inhibiting both myo-Ins biosynthesis and absorption. These underappreciated mechanisms may likely account for acquired, metabolic deficiency in inositol bioavailability.

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Selected Mineral Intakes of Adult African-Americans in the Washington, DC Area

Cited by 6 publications

References 9 publications

Phytate in foods and significance for humans: Food sources, intake, processing, bioavailability, protective role and analysis

Phytate in foods and significance for humans: Food sources, intake, processing, bioavailability, protective role and analysis

Inositols Depletion and Resistance: Principal Mechanisms and Therapeutic Strategies

Nutritional and Acquired Deficiencies in Inositol Bioavailability. Correlations with Metabolic Disorders

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