Selected‐Control Fabrication of Multifunctional Fluorescent–Magnetic Core–Shell and Yolk–Shell Hybrid Nanostructures

Abstract

The selected-control preparation of uniform core-shell and yolk-shell architectures, which combine the multiple functions of a superparamagnetic iron oxide (SPIO) core and europium-doped yttrium oxide (Y(2)O(3):Eu) shell in a single material with tunable fluorescence and magnetic properties, has been successfully achieved by controlling the heat-treatment conditions. Furthermore, the shell thickness and interior cavity of SPIO@Y(2)O(3):Eu core-shell and yolk-shell nanostructures can be precisely tuned. Importantly, as-prepared SPIO@Y(2)O(3):Eu yolk-shell nanocapsules (NCs) modified with amino groups as cancer-cell fluorescence imaging agents are also demonstrated. To the best of our knowledge, this is the first report on the selected-control fabrication of uniform SPIO@Y(2)O(3):Eu core-shell nanoparticles and yolk-shell NCs. The combined magnetic manipulation and optical monitoring of magnetic-fluorescent SPIO@Y(2)O(3):Eu yolk-shell NCs will open up many exciting opportunities in dual imaging for targeted delivery and thermal therapy.

Synthesis and characterization of sub-micrometer SiO2@NaYF4:Yb/Er beads and NaYF4:Yb/Er capsules for biomedical applications

“…3 show the amorphous SiO 2 @Y(OH)CO 3 :Yb/Er composite and crystalline SiO 2 @NaYF 4 :Yb/Er, respectively. The amorphous nature of SiO 2 @Y(OH)CO 3 :Yb/Er is consistent with previous reports [12,22]. Solvothermal reaction successfully converted the amorphous phase to crystalline phase of 16-0334) suggesting a mixture of both the phases.…”

“…The as-prepared silica particles were of uniform spherical morphology, and well dispersed in water with size of ~305 nm. A uniform amorphous Y(OH)CO 3 :Yb/Er shell was synthesized to obtain SiO 2 @Y(OH)CO 3 [22] so the SiO 2 @Y(OH)CO 3 :Yb/Er composite particles retain spherical morphology with good dispersion as can be seen from Fig.2(b).…”

Coordination polymer core/shell structures: Preparation and up/down-conversion luminescence

“…According to the Fig. 3b (right), it can be clearly observed that europium atoms were dominant at the edge of the nanosphere, and gadolinium atoms were abundant at the center of the nanoparticles, which was a typical tendency of the CP core/shell structures [26,30]. From the Fig.…”

Lanthanide‐doped hollow nanomaterials as theranostic agents

“…The procedure involves four steps: pre‐preparation of Fe 3 O 4 spheres, coating the Fe 3 O 4 core with silica layer and NaLuF 4 shell, and subsequently elimination of the SiO 2 middle layer [Figure (I)]. The outer shell can be substituted by other lanthanide‐doped UC or DC nanophosphors ,. Liu et al designed superparamagnetic iron oxide (SPIO)@Y 2 O 3 :Eu 3+ nanorattles with controllable shell thickness and inner voids .…”