Select appropriate wound dressings by matching the properties of the dressing to the type of wound

Writers, Adis Medical

doi:10.1007/s40267-014-0125-5

Cited by 6 publications

(7 citation statements)

References 13 publications

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“…59,60 Nowadays, traditional gauze dressings are no longer the only available wound care choice, and various types of newer dressings in the form of hydrogels, sponges, foams, fibers, and films are on the market. 61 The current challenge of the conventional wound treatment approaches and existing products is their inability to restore the full anatomy and physiology of the native host's skin in the injured area or the lack of skin appendage regeneration. 62,63 The ongoing progress of versatile bioactive glasses in regenerative medicine is bringing hope to restore organ functionality fully.…”

Section: T H Imentioning

confidence: 99%

“…The duration of each stage varies depending on the wound type and severity. 61 (I) Hemostasis: the first stage (hemostasis) is the body's immediate response to damage. In this phase, coagulation cascade and vasoconstriction occurs that last a few minutes to stop bleeding at the site of the injury, and platelet activation promotes the formation of a fibrin clot.…”

Section: Structure and Functions Of The Skinmentioning

confidence: 99%

“…Prior to selecting a dressing, an accurate wound assessment is necessary to consider the presence of tissue necrosis, infection, and amount of wound exudate. 61 Necrotic tissue is a nonviable tissue that hinders essential cell movements for granulation tissue formation. So, wound debridement is a clinically significant intervention.…”

Section: Structure and Functions Of The Skinmentioning

confidence: 99%

“…As shown in Figure , wound repair proceeds in four distinct but overlapping stages: (I) hemostasis, (II) inflammation, (III) proliferation, and (IV) remodeling. The duration of each stage varies depending on the wound type and severity Hemostasis : the first stage (hemostasis) is the body’s immediate response to damage.…”

Section: Wound Classification and Healing Phasesmentioning

confidence: 99%

“…The selection of appropriate wound dressing depends on many interrelated factors from the type of wound and its environment to wound dressing characteristics. Prior to selecting a dressing, an accurate wound assessment is necessary to consider the presence of tissue necrosis, infection, and amount of wound exudate . Necrotic tissue is a nonviable tissue that hinders essential cell movements for granulation tissue formation.…”

Section: Journey Of Traditional To Advanced Wound Dressingsmentioning

confidence: 99%

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Bioactive Glasses: A Promising Therapeutic Ion Release Strategy for Enhancing Wound Healing

Mehrabi

Mesgar

Mohammadi

2020

ACS Biomater. Sci. Eng.

112

108

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The morbidity, mortality, and burden of burn victims and patients with severe diabetic wounds are still high, which leads to an extensively growing demand for novel treatments with high clinical efficacy. Biomaterial-based wound treatment approaches have progressed over time from simple cotton wool dressings to advanced skin substitutes containing cells and growth factors; however, no wound care approach is yet completely satisfying. Bioactive glasses are materials with potential in many areas that exhibit unique features in biomedical applications. Today, bioactive glasses are not only amorphous solid structures that can be used as a substitute in hard tissue but also are promising materials for soft tissue regeneration and wound healing applications. Biologically active elements such as Ag, B, Ca, Ce, Co, Cu, Ga, Mg, Se, Sr, and Zn can be incorporated in glass networks; hence, the superiority of these multifunctional materials over current materials results from their ability to release multiple therapeutic ions in the wound environment, which target different stages of the wound healing process. Bioactive glasses and their dissolution products have high potency for inducing angiogenesis and exerting several biological impacts on cell functions, which are involved in wound healing and some other features that are valuable in wound healing applications, namely hemostatic and antibacterial properties. In this review, we focus on skin structure, the dynamic process of wound healing in injured skin, and existing wound care approaches. The basic concepts of bioactive glasses are reviewed to better understand the relationship between glass structure and its properties. We illustrate the active role of bioactive glasses in wound repair and regeneration. Finally, research studies that have used bioactive glasses in wound healing applications are summarized and the future trends in this field are elaborated.

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