Seizure disorders, depression, and health-related quality of life

Depression and symptoms affect quality of life in psychogenic nonepileptic seizures

“…However, patients with PNES report worse QOL in comparison to both epilepsy and depression norms. 21 These findings underscore the importance of evaluating and treating mood status in patients with PNES with the hopes of improving QOL. Though it is important to make a diagnosis of PNES, merely presenting the diagnosis of PNES alone is not enough, as postdiagnosis frequency decreases are not maintained long term.…”

Attachment style, relationship quality, and psychological distress in patients with psychogenic non-epileptic seizures versus epilepsy

“…[4] PNES and epilepsy are both associated with higher levels of anxiety and depression than those found in the general population. [5] However, patients with PNES consistently report poorer HRQoL and higher levels of anxiety and depression than those with epilepsy. [6] To date, very little is known about whether the causes of psychopathology in patients with these two different seizure disorders are identical or whether they differ -for instance because of the well-recognised higher rates of previous trauma, neglect, and family dysfunction reported by patients with PNES that are considered important predisposing factors for this disorder.…”

Dissociative experiences and quality of life in patients with non-epileptic attack disorder

“…Specifically, evidence suggests that depression, somatic symptoms, adverse events and personality factors can have a greater impact than attack frequency on patients' day to day functioning [10][11][12][13]. However, studies which attempt to produce a model to explain the factors that are associated with HRQoL only account for 65% of the variance at best [10].…”