From December 3, 2005 to May 18, 2006, a water injection-induced seismicity test was conducted on DuPont test well 1# for about six months by China Earthquake Administration. To the vertical injected well, 11 water injection processes were conducted on four depth intervals, including middle Shahejie3, the top of the upper Shahejie3, the bottom of the upper Shahejie3 and Shahejie2, with the vertical span from 1 464 m to 3 034 m. Monitoring stations has been run throughout the procedure. From the recorded data, there were 5 090 events being picked out manually, 274 events located. It indicates that the energy of seismic signal is very small, and the largest magnitude is no more than M L 0.5. And also, the major energy is centered on the vertical component, while amplitude of the other horizontal components is very small. From the start of water injection, the number of seismic events varied with time. And the event was most frequent in the period of upper Shahejie3 injection. The distribution of events extended from the injected well to the outside with time, and the direction of events distribution rotated in different injected interval. Of which, in the low permeability interval, events trend close to the direction of principal compressive stress direction; while in higher permeability interval, they trend close to the predominant seepage direction.