Segurança, Eficácia e Protocolo de Dose de Metoprolol para Redução de Frequência Cardíaca em Pacientes Pediátricos Externos que Passaram por Angiografia Cardíaca por TC

Nunes, Mariana De Oliveira; Witt, Dawn; Casey, Susan A.; Stanberry, Larissa; Caye, David; J.Chu, Bradford; Lindberg, B. Jana; Lesser, John R.; Han, Bo

doi:10.36660/abc.20190892

Cited by 1 publication

(1 citation statement)

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“…Current papers describe an average reduction in heart rate of around 19 beats per minute or 23% under beta-blockers 27 . However, the mean age in the aforementioned study was 13 years old.…”

Section: Discussionmentioning

confidence: 99%

Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease

Kravchenko

Hart

Garbe

et al. 2022

Sci Rep

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To explore the image quality and radiation dose of dual source high-pitch cardiac computed tomography with tailored contrast injection protocols for pediatric congenital heart disease patients (CHD). In total, 27 infants with CHD (median age 109 days [IQR 6–199]) were retrospectively analyzed regarding dose length product (DLP) and effective dose (ED) after undergoing cardiothoracic CT imaging. Scan parameters were adjusted on a dual source/detector CT (DSCT) to minimize radiation dose while maintaining adequate quality. Image acquisition was performed at 70% of the R–R interval. Dose reducing measures included prospective electrocardiogram gating, utilizing slow injection velocities and foregoing bolus tracking during contrast injection. Image quality was assessed for artefacts, vessel definition, and noise on a 5-point scale (1 non-diagnostic, 5 excellent). Series were scored on a 0-to-3-point scale regarding answered clinical questions (0 non-diagnostic, 3 all clinical questions could be answered). The median DLP was 5.2 mGy*cm (IQR 3.5–7.8) leading to a median ED of 0.20 mSv (IQR 0.14–0.30). On average the acquired images scored 13.3 ± 2.1 (SD) out of a maximum 15 points with an intraclass correlation coefficient (ICC) of 0.94. All acquired series were able to fully answer all clinical questions scoring maximum points (ICC 1.0). Dual source high pitch CT protocols combined with custom contrast agent injection protocols in pediatric patients with CHD delivered sufficiently high diagnostic imaging quality combined with low submilisievert radiation doses. Prospective high pitch imaging is a reliable method for depiction of cardiac anatomy even in very young pediatric CHD patients with elevated heart rates.

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Section: Discussionmentioning

confidence: 99%