Segmentation of scarred and non-scarred myocardium in LG enhanced CMR images using intensity-based textural analysis

Abstract

The Late Gadolinium (LG) enhancement in Cardiac Magnetic Resonance (CMR) imaging is used to increase the intensity of scarred area in myocardium for thorough examination. Automatic segmentation of scar is important because scar size is largely responsible in changing the size, shape and functioning of left ventricle and it is a preliminary step required in exploring the information present in scar. We have proposed a new technique to segment scar (infarct region) from non-scarred myocardium using intensity-based texture analysis. Our new technique uses dictionary-based texture features and dc-values to segment scarred and non-scarred myocardium using Maximum Likelihood Estimator (MLE) based Bayes classification. Texture analysis aided with intensity values gives better segmentation of scar from myocardium with high sensitivity and specificity values in comparison to manual segmentation by expert cardiologists.

Radiomics of Non-Contrast-Enhanced T1 Mapping: Diagnostic and Predictive Performance for Myocardial Injury in Acute ST-Segment-Elevation Myocardial Infarction

“…The use of native T1 mapping for post-acute MI without use of contrast would be of major clinical use, in that it would not only be safer in patients with kidney impairment and would shorten the scan time (by avoiding contrastbased techniques) but would also potentially allow for an early accurate stratification of those acute patients in need of more aggressive treatment (30). Furthermore, TA based on T1 mapping, as it includes more information, may be used to assess the high risk of arrhythmia patients to implant ICD (31,32).…”

Evaluation of Sudden Cardiac Death, Using Cardiovascular Magnetic Resonance

“…PIZ was defined as area with an SI between 2 and 3 SD above SI of remote myocardium, normalized as a percentage of total infarct zone (area with an SI of > 2 SD above remote myocardium). Roes et al [79] found that PIZ was the strongest predictor for spontaneous VT. Based on the potential limitation of using the peak SI of remote myocardium to define PIZ, core infarct and PIZ were based exclusively on the maximum SI in the hyperenhanced area (core SI ≥ 50% of maximal SI, grey zone 35% ≤ SI < 50% of maximum SI) [80,81]. However, at the moment there are no data about the definite role of PIZ in the SCD prediction.…”

Texture analysis of cardiac cine magnetic resonance imaging to detect nonviable segments in patients with chronic myocardial infarction

“…Previous studies reported an improvement in detection of scarred myocardium on LGE images when combining texture and intensity features . Texture analysis was also used to create probability maps using LGE images that aid the visual inspection of the myocardial tissue .…”