Abstract:Background:Thoracic spinal anesthesia has been used for laparoscopic cholecystectomy and abdominal surgeries, but not in breast surgery. The present study compared this technique with general anesthesia in breast cancer surgeries.Materials and Methods:Forty patients were enrolled in this comparative study with inclusion criteria of ASA physical status I-III, primary breast cancer without known extension beyond the breast and axillary nodes, scheduled for unilateral mastectomy with axillary dissection. They wer… Show more
“…Nevertheless, we were able to find in literature only one randomized study mentioning the use of STSA in surgical procedures involving the breast and the axillary region. 15 …”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, though three recent series from our Institution conducted on a large population of elderly patients already illustrated the feasibility, efficacy and safety of thoracic continuous spinal anesthesia (TCSA) in abdominal and urological surgery, 12–14 the secure and reliable use of STSA in patients undergoing major breast surgery and axillary lymph node dissection (ALND) was described only by Elakany et al 15 …”
Purpose
Few studies have described segmental thoracic spinal anesthesia (STSA) as primary anesthesiologic method in breast and axillary surgery, documenting the association of intrathecal local anesthetics and opioids. This case series reports an opioid-free scheme of STSA in four elderly patients undergoing major breast and axillary oncological surgery.
Patients and Methods
STSA was performed in three female patients undergoing unilateral mastectomy ± axillary lymph node dissection (ALND) or sentinel lymph node biopsy for invasive ductal carcinoma and in one male patient undergoing ALND for melanoma metastases. The level of needle insertion was included between T6-8, via a median or paramedian approach. Midazolam (2 mg) and ketamine (20 mg) were used as adjuvants for intrathecal sedation, followed by the administration of hypobaric ropivacaine 0.25% at a dose of 8 mg. The level of sensory blockade achieved was comprised between C2-3 and T11-12. Postoperative analgesia was maintained through continuous intravenous administration of Ketorolac by an elastomeric pump (90 mg over 24 hrs.).
Results
Spinal anesthesia was completed without complications in all patients. Conversion to general anesthesia (GA) and perioperative intravenous sedation were not required. No major postoperative complications and no episodes of postoperative nausea and vomiting (PONV) were reported. No rescue analgesic was administered. All patients were discharged in postoperative day 2 and are alive at 30, 29, 27 and 13 months after surgery, respectively. High grade of satisfaction on the anesthesiologic method was expressed by all cases.
Conclusion
STSA with local anesthetic plus midazolam and ketamine might be considered a safe and effective alternative to GA, even in surgeries involving the breast and axillary region, particularly in elderly and frail patients. Larger prospective studies are required to validate these findings.
“…Nevertheless, we were able to find in literature only one randomized study mentioning the use of STSA in surgical procedures involving the breast and the axillary region. 15 …”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, though three recent series from our Institution conducted on a large population of elderly patients already illustrated the feasibility, efficacy and safety of thoracic continuous spinal anesthesia (TCSA) in abdominal and urological surgery, 12–14 the secure and reliable use of STSA in patients undergoing major breast surgery and axillary lymph node dissection (ALND) was described only by Elakany et al 15 …”
Purpose
Few studies have described segmental thoracic spinal anesthesia (STSA) as primary anesthesiologic method in breast and axillary surgery, documenting the association of intrathecal local anesthetics and opioids. This case series reports an opioid-free scheme of STSA in four elderly patients undergoing major breast and axillary oncological surgery.
Patients and Methods
STSA was performed in three female patients undergoing unilateral mastectomy ± axillary lymph node dissection (ALND) or sentinel lymph node biopsy for invasive ductal carcinoma and in one male patient undergoing ALND for melanoma metastases. The level of needle insertion was included between T6-8, via a median or paramedian approach. Midazolam (2 mg) and ketamine (20 mg) were used as adjuvants for intrathecal sedation, followed by the administration of hypobaric ropivacaine 0.25% at a dose of 8 mg. The level of sensory blockade achieved was comprised between C2-3 and T11-12. Postoperative analgesia was maintained through continuous intravenous administration of Ketorolac by an elastomeric pump (90 mg over 24 hrs.).
Results
Spinal anesthesia was completed without complications in all patients. Conversion to general anesthesia (GA) and perioperative intravenous sedation were not required. No major postoperative complications and no episodes of postoperative nausea and vomiting (PONV) were reported. No rescue analgesic was administered. All patients were discharged in postoperative day 2 and are alive at 30, 29, 27 and 13 months after surgery, respectively. High grade of satisfaction on the anesthesiologic method was expressed by all cases.
Conclusion
STSA with local anesthetic plus midazolam and ketamine might be considered a safe and effective alternative to GA, even in surgeries involving the breast and axillary region, particularly in elderly and frail patients. Larger prospective studies are required to validate these findings.
“…In contrast, Elakany et al . [ 16 ] proved that hypotension and bradycardia developed in 15% of cases that received segmental thoracic spinal anesthesia. However, our findings coincide with those of Imbelloni L E,[ 15 ] who used a similarly reduced dose of hyperbaric bupivacaine (7.5 mg) given in combination with fentanyl, and achieved less hemodynamic instability and fewer adverse events.…”
“…3 Regional anesthesia provides effective anesthesia and analgesia in the perioperative period. Various regional anesthetic techniques have been used for breast surgeries, like local wound infiltration, cervical epidural, 4 thoracic epidural anesthesia, 5 thoracic paravertebral block, 6 thoracic spinal anesthesia, 7 interpleural block 8 etc.…”
Background: Modified radical mastectomies (MRM) is conventionally done under general anaesthesia. Various regional anesthetic techniques have also been used to provide effective analgesia in the perioperative period. This study was to compare the analgesia and hemodynamic effects of bupivacaine and ropivacaine when used in thoracic epidural for modified radical mastectomy. Methods: 67 patients scheduled for MRM were enrolled in the study. They were randomized into two groups -Group R and Group B. Through an epidural catheter inserted at T5-T6, the patients in Group R received 12ml of 0.5% ropivacaine whereas those in group B received 12 ml of 0.5% bupivacaine.After one hour, 4 ml of the test drug was repeated every 30 minutes till the end of surgery. Intraoperative hemodynamic, side effects and postoperative VAS scores were recorded. 60 patients completed the study and their results were analyzed. Results: Statistically significant differences were observed in heart rate and mean arterial pressure between the two groups at various time intervals. The mean time of onset of the analgesia was shorter in Ropivacaine group 12.90±2.04mins, 19.27±5.51 in the Bupivacaine group. Post operative VAS scores were similar in both the groups. Patients in both groups were equally satisfied. Conclusion: High thoracic epidural is a safe and reliable alternative to general anaesthesia in modified radical mastectomies. Ropivacaine 0.5% is preferred due to its faster onset, better hemodynamic stability and good analgesia.
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