Segmental colitis associated with diverticula: a prospective study

Imperiali, G.; Meucci, G.; Alvisi, C; Fasoli, R.; Ferrara, A.; Girelli, C.M.; Rocca, Francesco La; Saibeni, Simone; Minoli, Giorgio

doi:10.1111/j.1572-0241.2000.01943.x

Cited by 95 publications

(55 citation statements)

References 7 publications

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“…7 This pattern was termed diverticular colitis, 8 crescentic fold disease, 9 diverticular disease-associated colitis, 10,11 isolated sigmoiditis, and segmental colitis associated with diverticulosis. [12][13][14] However, this terminology applies only to patients with diverticulitis without an established diagnosis of IBD, while only a small minority of these patients will progress to classic IBD. 10,15,16 Two studies approached the question of a possible mutual interaction between IBD and diverticulosis on the development and nature of inflammation; Meyers et al 17 suggested that CD in the setting of diverticulosis may lead to development of diverticulitis.…”

Section: Discussionmentioning

confidence: 99%

Long-standing colonic inflammation is associated with a low prevalence of diverticuli in inflammatory bowel disease patients

Lahat

Avidan

Bar‐Meir

et al. 2007

Inflammatory Bowel Diseases

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Section: Discussionmentioning

confidence: 99%

Long-standing colonic inflammation is associated with a low prevalence of diverticuli in inflammatory bowel disease patients

Lahat

Avidan

Bar‐Meir

et al. 2007

Inflammatory Bowel Diseases

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“…In 2000, Imperiali et al found retrospective prevalence of 0.36% of SCAD in a total of 5,457 patients recorded in five Italian endoscopic centers, with prevalence falling afterwards to 0.25% as six patients were soon discharged to other diagnosis [7]. Endoscopic prevalence was therefore 1.15% of patients with diverticulosis, with mean age of 66.5 years [7].…”

Section: Epidemiologymentioning

confidence: 97%

Segmental Colitis Associated with Diverticulosis: Complication of Diverticular Disease or Autonomous Entity?

Tursi

2010

Dig Dis Sci

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Segmental colitis associated with diverticulosis (SCAD) is a disease that affects colon harboring diverticula, mostly located in the sigmoid region. It has been considered a rare disease for many years, but new studies may contribute to easier recognition. Although its pathogenesis is not yet well defined, in the past SCAD has been considered a complication of diverticular disease, whilst new endoscopic, histological, and clinical data have encouraged the concept that SCAD includes pathogenetic and therapeutic aspects peculiar to inflammatory bowel diseases. We therefore describe herein current knowledge about this disease, and why it can be considered a truly autonomous entity instead of a complication of diverticular disease.

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“…In addition to other pelvic disease and to infectious or inflammatory bowel disease, special forms of inflammatory or otherwise abnormal mucosa coexisting with diverticulosis must be considered, in order to avoid a too liberal ‘definition’ of diverticulitis, e.g. NSAID colitis, ischemia [7], diverticular colitis [8,9,10,11,12], mesenteric inflammatory veno-occlusive disease [13], coexistence of Crohn’s disease and diverticulosis or diverticulitis [14,15,16,17], and prolapsing mucosal folds in diverticular disease [18,19]. Not taking care for these differentiations makes it very difficult to compare patients, rationales and results from the literature.…”

Section: What Is Recurrent Diverticulitis?mentioning

confidence: 99%

The Gastroenterologist’s View

Lembcke¹

2012

Dig Dis

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The traditional view that recurrent episodes of diverticulitis lead to progressively complicated disease resulting in a disadvantageous course, more difficult, complicated operations and lethal outcomes did not stand the test of evidence. Only a minority of patients with acute diverticulitis will ever require surgery, and if so, this occurs during or early after the first episode. Complications and recurrence of disease after surgery are enumerable. Strong indicators favoring sigmoid colectomy are major abscess, free air, and fistula, i.e. perforating disease. This occurs predominantly at the initial presentation, frequently in younger or immunosuppressed patients. Important differential diagnoses must be considered both for initial diagnosis of diverticulitis and for recurrent episodes. Conservative management of recurrent diverticulitis is safe and best guided by gastroenterological expertise. Sophisticated ultrasound experience as a part of this competence allows detailed evaluation of the local status and the best evidence in the literature for diagnosing diverticulitis is on US. In practice, however, the question of perforating diverticulitis is adequately answered by subtle CT scan. Medical therapy is usually the treatment of choice for recurrent diverticulitis. Avoidance of drugs bearing the hazard of perforation (e.g. NSAIDs) is emphasized, and smoking is strongly discouraged. A mathematical model based on published data shows that patients with recurrent diverticulitis overall (only) profit from surgery if they are hit by four episodes during the course of disease. This is where theory and reality (should) meet.

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Segmental colitis associated with diverticula: a prospective study

Cited by 95 publications

References 7 publications

Long-standing colonic inflammation is associated with a low prevalence of diverticuli in inflammatory bowel disease patients

Long-standing colonic inflammation is associated with a low prevalence of diverticuli in inflammatory bowel disease patients

Segmental Colitis Associated with Diverticulosis: Complication of Diverticular Disease or Autonomous Entity?

The Gastroenterologist’s View

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