Segmental Arterial Mediolysis: A Systematic Review of 85 Cases

Shenouda, Michael; Riga, Celia; Naji, Yaser; Renton, Sophie

doi:10.1016/j.avsg.2013.03.003

Cited by 97 publications

(183 citation statements)

References 51 publications

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“…SAM affects all age groups. In a recent systematic review there was a slight male predominance of 1,5:1 [6].…”

Section: Discussionmentioning

confidence: 99%

“…The most common presentation however, is non-specific abdominal pain and flank pain. A more acute presentation involves shock owing to an intra-abdominal hemorrhage (as in our patient), occurring in less than 30 percent of the cases, but with a high mortality rate of 50% [6,7]. Other presentations are central nervous system involvement with stroke or headaches and renal involvement with hematuria [8].…”

Section: Discussionmentioning

confidence: 99%

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A rare case of segmental arterial mediolysis

Simons¹,

Simons²,

J.G³

2015

Clin Case Rep Rev

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“…SAM affects all age groups. In a recent systematic review there was a slight male predominance of 1,5:1 [6].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A rare case of segmental arterial mediolysis

Simons¹,

Simons²,

J.G³

2015

Clin Case Rep Rev

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“…It accounts for 18% of all SAM lesions. 3) Its frequent sites are the internal carotid and vertebral arteries. 3) SAM affects multiple arteries.…”

Section: Discussionmentioning

confidence: 99%

“…Before 2012, 15 patients were reported. 3) In only nine of these, pathologically verified as SAM simultaneously occurring both intracranial and -peritoneal vascular lesions. 3) In this study, we examined the pathogenesis of intracranial artery dissection based on histopathological findings in four autopsy cases of IVA-rupture-related subarachnoid hemorrhage complicated by intraperitoneal hemorrhage.…”

Section: Introductionmentioning

confidence: 99%

Pathomorphological Examination of Patients with the Simultaneous Rupture of Dissecting Intracranial Vertebral and Intraperitoneal Arteries: Involvement of Segmental Arterial Mediolysis in Intracranial Artery Dissection

Kageyama

Mukai

2018

JNET

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Objective: To examine the involvement of segmental arterial mediolysis (SAM) in intracranial artery dissection. Methods:In four autopsy cases of subarachnoid hemorrhage related to the rupture of the intracranial vertebral artery (IVA) with intraperitoneal hemorrhage, we calculated the extent of arterial dissection using elastica van Gieson staining from the tissue sections of the left/right IVAs and intraperitoneal arteries (IPAs), and examined the properties of the vascular smooth muscle and responses of mesenchymal cells using immunostaining with anti-α smooth muscle antibody (SMA) and anti-S100A4 antibodies. Results:The length of the adventitia at the site of IVA rupture was ≤2.4 mm, and that of disruptions of the internal elastic lamina was 5.4-11 mm. The IVA/IPA rupture sites showed acute arterial dissection. In the blood vessels at the sites of dissection, defect/necrosis of the vascular smooth muscle, which are characteristic of SAM, were noted. In three cases, the topical infiltration of mesenchymal cells was observed in the adventitia at the dissected site of the ruptured IVA. In all cases, dissection of unruptured intracranial or -peritoneal arteries was also present. Its pathological properties vary from acute to old dissection. Conclusion:Autopsy revealed SAM-related systemic multiple arterial dissection in all cases, suggesting the involvement of SAM in the development of intracranial artery dissection.

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“…The main clinical symptom is abdominal pain caused by abdominal hemorrhage or arterial infarction (3). Aneurysm rupture or bowel infarction requires surgical or interventional radiological therapy.…”

Section: Introductionmentioning

confidence: 99%

Segmental arterial mediolysis mimics systemic vasculitis

et al. 2016

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Segmental arterial mediolysis (SAM) is a rare, nonarteriosclerotic, noninflammatory vascular disease and mostly affects medium-to-large sized abdominal arteries as well as presents with hemorrhages in the abdominal cavity. We report the case of a patient with SAM of the celiac, right renal, jejunal branch of the superior mesenteric, left gastric, and splenic arteries who was diagnosed by excluding other causes and in whom transcatheter embolization was performed in two different sessions, but he died because of an undefined reason. SAM mimics systemic vasculitis and causes abdominal pain; it should be considered because abdominal hemorrhage or arterial infarction can result in death.

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Segmental Arterial Mediolysis: A Systematic Review of 85 Cases

Cited by 97 publications

References 51 publications

A rare case of segmental arterial mediolysis

A rare case of segmental arterial mediolysis

Pathomorphological Examination of Patients with the Simultaneous Rupture of Dissecting Intracranial Vertebral and Intraperitoneal Arteries: Involvement of Segmental Arterial Mediolysis in Intracranial Artery Dissection

Segmental arterial mediolysis mimics systemic vasculitis

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