Segmental Aplasia of the Uterine Horn with Ipsilateral Renal Agenesis in a Cat

Abstract

ABSTRACT. A nine-month-old domestic short haired cat was admitted with the history of acute vomiting, depression and shivering. Abdominal ultrasonography revealed minimum enlargement of the right uterine horn filled with anechoic fluid. On excretory urography, functionally and anatomically normal, enlarged left kidney was found, but right kidney was absent. It was preliminary diagnosed as hydrometra with right renal agenesis. Aiming at the correction of hydrometra, we performed ovariohysterectomy. During spaying, we found a missing segment of distal part of the right uterine horn and absence of ipsilateral kidney and ureter. Compressed uterine structure and segmental aplasia of right uterine horn were found in histopathological investigation. Taken together, it was diagnosed as a segmental aplasia of uterine horn with ipsilateral renal agenesis. KEY WORDS: feline, renal agenesis, uterine segmental aplasia.J. Vet. Med. Sci. 70(6): 641-643, 2008 A nine-month-old, intact female, domestic short haired cat was admitted with the history of acute vomiting, depression and shivering for three days. The rise of temperature (40°C) was recorded, and there was azotemia (BUN: 74.0 mg/dl, creatinine: 4.5 mg/dl) on the routine blood screening test. Abdominal radiography showed absence of the right kidney, while the left one was enlarged (3.2 × length of the 2nd lumbar vertebra). Incidentally, there was unilateral sacralization of the 7th lumbar vertebra with articulation between right transverse process and the ilium at same side. Abdominal ultrasonography demonstrated minimum enlargement of the right uterine horn (12.5 mm in diameter) filled with anechoic fluid. Excretory urography revealed the normal shape and opacification pattern of the left kidney meaning the normal physiological activities, however, the right kidney was absent (Fig. 1). In spite of unknown causes of azotemia, this patient was recovered through 2 days supportive treatment including fluid therapy and diuretics, and then received ovariohysterectomy under general anesthesia to prevent further deterioration of the uterine horn. Surprisingly, there were no the distal part of the right uterine horn, the right kidney and the right ureter during surgery (Fig. 2A). The remnant of the right uterine horn was tortuous and dilated with fluid, and was not connected to the body of the uterus. The left uterine horn was intact and there was a small notch as vestige at the body of uterus (Fig. 2B). Gross and histopathologic examination revealed that both ovaries, fallopian tubes and the left uterine horn were normal (Fig. 3A-C There is unilateral sacralization of the 7th lumbar vertebra with articulation between right transverse process and the ilium at same side (arrow).

Aplasia Unilateral De Corno Uterino Associada À Piometra E Cisto Parovariano Unilateral Em Gata: Relato De Caso

“…A atividade cíclica geralmente está preservada, visto que os ovários possuem origem embriológica distinta (VINCE et al, 2011;AGUIRRA et al, 2014); em consonância com estes dados, os ovários apresentavam-se funcionais e inalterados anatomicamente. As aplasias uterinas isoladas não produzem sinais clínicos, constituindo um achado acidental em laparotomias exploratórias, necropsias ou ovariosalpingohisterectomias eletivas ou curativas, este último condizente com o caso em questão (CHANG, 2008;MCINTYRE, 2010;AGUIRRA et al, 2014).…”

“…O desenvolvimento incompleto dos ductos paramesonéfricos durante a vida embrionária pode se manifestar como uma série de anomalias congênitas em tubas uterinas, corpo e cornos uterinos e parte cranial da vagina (SCHULMANA & BOLTONB, 1997;OH et al, 2005;CHANG et al, 2008;GRADELA et al, 2013;AGUIRRA et al, 2014). Um exemplo é a aplasia de corno uterino, condição que pode acometer ambos os cornos (aplasia uterina total), somente um corno (aplasia uterina parcial, unilateral ou útero unicorno), ou uma parte de um corno (aplasia segmentar) (VINCE et al, 2011).…”

“…Muitas vezes o diagnóstico destas enfermidades consiste de um achado acidental em laparotomias exploratórias, ovariosalpingohisterectomias ou exames post mortem (CHANG et al, 2008;AGUIRRA et al, 2014), uma vez que dificilmente sinais clínicos estão presentes (CHANG et al, 2008).…”

“…A aplasia uterina pode estar associada à hidrometra (OH et al, 2005), complexo endometrial cístico/ piometra (SCHULMANA E BOLTONB, 1997), condições hermafroditas ou ainda à agenesia renal ipsilateral, em decorrência do desenvolvimento interligado dos sistemas reprodutivo e urinário (CHANG et al, 2008;MCINTYRE, 2010).…”

Agenesia renal unilateral e criptorquidismo ipsilateral em um felino: relato de caso

“…A coexistência entre malformações urinárias e genitais tem sido identificada mais frequentemente em fêmeas do que em machos da espécie felina. (Chang et al, 2008;Narasimhan e Absar, 2010;Carvallo et al, 2012).…”