Segmental and global longitudinal strain and strain rate based on echocardiography of 1266 healthy individuals: the HUNT study in Norway

Dalen, Håvard; Thorstensen, Anders; Aase, Svein Arne; Ingul, Charlotte Björk; Torp, Hans; Vatten, Lars J.; Støylen, Asbjørn

doi:10.1093/ejechocard/jep194

Cited by 279 publications

(337 citation statements)

References 31 publications

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“…In a cohort of 56 patients, longitudinal strain was decreased along with increased LV torsion. The authors also found a correlation with serum levels of aminoterminal propeptide of procollagen I/III and tissue inhibitor of matrix metalloproteinase, suggesting a modification of the myocardial collagen turnover and fibrotic process which could alter LV systolic function [29].…”

Section: Systolic Function Assessed With Ste In Patients Undergoinmentioning

confidence: 88%

Speckle-Tracking analysis of left ventricular systolic function in the intensive care unit

Cinotti¹,

Delater²,

Fortuit³

et al. 2015

Anaesthesiol Intensive Ther

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Speckle-tracking analysis is a new available tool in order to assess left ventricular function in cardiology. Its novelty relies on the technological ability to track natural acoustic markers (known as speckle) within the myocardium during the cardiac cycle. This technology allows the evaluation of myocardium strain during systole and diastole. To date, global longitudinal strain (GLS) has been extensively studied in cardiology. It is now well established that GLS is more sensitive than left ventricular ejection fraction with 2D echocardiography in detecting systolic function impairment. It is also superior to left ventricular ejection fraction in the prediction of major cardio-vascular events. In the intensive care unit (ICU) setting, data are scarce. In experimental model and human studies in septic shock, speckle-tracking analysis suggests that GSL is impaired along with preserved left ventricular ejection fraction. Recent data also suggest that GLS impairment could predict in-ICU mortality in septic shock. In severe subarachnoid haemorrhage patients, speckle-tracking analysis could be more sensitive in detecting stress cardiomyopathy. However, there are many gaps to fill in the critically ill patient. For instance, the influence of mechanical ventilation on GLS is not fully elucidated, and there are, to date, too few data to exactly assess potential GLS alterations on the patient's outcome. Nonetheless, this new tool provides objective and sensitive data with acceptable intra and inter-observer variability and may be of primary interest in the evaluation of left-ventricular systolic function in the ICU.

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Section: Systolic Function Assessed With Ste In Patients Undergoinmentioning

confidence: 88%

Speckle-Tracking analysis of left ventricular systolic function in the intensive care unit

Cinotti¹,

Delater²,

Fortuit³

et al. 2015

Anaesthesiol Intensive Ther

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show abstract

“…It is known that Sm, SS, and SSR are different in particular walls of LV. In the HUNT study, which investigated the distribution of longitudinal strain and strain rate in a healthy population of 1296 subjects, the authors did not find statistically important differences between basal, mid, and apical segments of anterior and inferior wall [15]. In the presented study, we evaluated patients with LAD stenosis confirmed in computed tomography or coronary catheterisation.…”

Section: Discussionmentioning

confidence: 95%

Transthoracic ultrasonic tissue indices identify patients with severe left anterior descending artery stenosis. Correlation with fractional flow reserve. Pilot study

et al. 2016

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A b s t r a c t Background and aim:The aim of this study was to evaluate the potential clinical application of ultrasonic tissue indices, with a focus on systolic strain (SS) and systolic strain rate (SSR) parameters derived from transthoracic echocardiography, in the assessment of left anterior descending artery (LAD) stenosis. Methods:The data of 30 patients with significant LAD stenosis were analysed. All patients underwent transthoracic echocardiography to obtain systolic myocardial velocity (Sm), longitudinal SS, and SSR from basal, mid, and apical segments of anterior and inferior walls in two-chamber apical view. Severity of LAD obstruction was measured by means of fractional flow reserve (FFR) during coronary catheterisation.Results: Systolic velocities, strain, and strain rate measured in basal, middle, and apical segments of the anterior left ventricular (LV) wall were lower when compared to those obtained from the corresponding, i.e. unaffected, inferior LV wall. There was a significant correlation between FFR and the value of SS, SSR characterising the apical LV segment of the anterior wall (r = -0.583, p = 0.01; r = -0.598, p = 0.01, respectively). Moreover, we found significant correlation between FFR and Sm in the mid-segment of the LV anterior wall (r = 0.611, p = 0.009). Conclusions:We conclude that SS and SSR obtained from the apical segment of the anterior LV wall may be related to the severity of LAD stenosis.

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“…Harwick describes strain values for all walls all levels at -18.6% (± 5.1) with the following regional strain values listed below [11]. Dalen et al described normal GLS as -17.4% (± 2.3) in women and -15.9% (± 2.3) [12]. Current 3D and 4D strain analyses can further identify stress patterns in multiple dimensions simultaneously.…”

Section: Discussionmentioning

confidence: 99%

“…All walls -18.6% ± 5.1 -20.2% ± 5.6 -18.7% ± 3.8 -17.0% ± 5.2 Table 1: Cardiac segments in Takotsubo Cardiomyopathy [12].…”

Section: All Levels Apical Mid Basalmentioning

confidence: 99%

Takotsubo Cardiomyopathy a Case Report: Ballooning outside the Apex?

Semien¹

2014

J Clin Exp Cardiolog

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Takotsubo's cardiomyopathy is characterized as per Mayo criteria by transient wall motion abnormalities involving the left ventricular apex and mid-ventricle in the absence of obstructive epicardial coronary artery disease and pheochromocytoma or myocarditis as well as new electrocardiographic abnormalities. Recent literature has suggested a variance in segments involved in this stress induced cardiomyopathy. This case illustrates not only classic left apical and mid-ventricular involvement but also a reduction in basal contractility (compared to normal strain numbers by segment) as measured by strain.

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Segmental and global longitudinal strain and strain rate based on echocardiography of 1266 healthy individuals: the HUNT study in Norway

Abstract: The reference values for global and segmental longitudinal strain and SR obtained from this population study are applicable for use in a wide clinical setting.

Cited by 279 publications

References 31 publications

Speckle-Tracking analysis of left ventricular systolic function in the intensive care unit

Speckle-Tracking analysis of left ventricular systolic function in the intensive care unit

Transthoracic ultrasonic tissue indices identify patients with severe left anterior descending artery stenosis. Correlation with fractional flow reserve. Pilot study

Takotsubo Cardiomyopathy a Case Report: Ballooning outside the Apex?

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