SEEI: spherical evolution with feedback mechanism for identifying epistatic interactions
De-yu Tang,
Yi-jun Mao,
Jie Zhao
et al.
Abstract:Background
Detecting epistatic interactions (EIs) involves the exploration of associations among single nucleotide polymorphisms (SNPs) and complex diseases, which is an important task in genome-wide association studies. The EI detection problem is dependent on epistasis models and corresponding optimization methods. Although various models and methods have been proposed to detect EIs, identifying EIs efficiently and accurately is still a challenge.
Results
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