Seed coordinates of a new COMS‐like 24 mm plaque verified using the FARO Edge

Cutsinger, S.E. McCauley; Furutani, Keith M.; Forsman, Renae M.; Corner, Stephen M.

doi:10.1120/jacmp.v16i6.5721

Cited by 6 publications

(4 citation statements)

References 4 publications

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“…The plaque's central axis (CAX) defines the

z

‐axis, with

x

and

y

coordinates transverse to the plaque. Plaques contain between 5 and 33 seeds, with positions and orientations provided in the online CLRP_EPv2 database based on earlier publications: TG‐129 report 2 (COMS 10–22 mm; BEBIG), Cutsinger et al 23 (COMS 24 mm), and Lespérance et al 14 (representative plaques: Cta, Sla, NlS, Ssa).…”

Section: Acquisition and Validation Methodsmentioning

confidence: 99%

“…The egs++ class library geometry module is used to develop the eye plaque models: COMS plaques with diameters (

D

) from 10 to 24 mm (in 2 mm increments), 2,23 BEBIG plaques with diameters from 12 to 20 mm (in 2 mm increments; simulated for the first time), and four different 16 mm diameter “representative” plaque models 1,14 . These representative plaque models were previously developed by Lespérance et al 14 to approximate different plaque models in use worldwide (for which exact dimensions and material specifications are not widely available and/or accurately known), and include “Short lip‐acrylic” (Sla), 24 “COMS‐thin acrylic” (Cta), 25 “No lip‐Silastic” (NlS), 26 and “Stainless steel‐acrylic” (Ssa) 27 .…”

Section: Acquisition and Validation Methodsmentioning

confidence: 99%

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Update of the CLRP eye plaque brachytherapy database for photon‐emitting sources

et al. 2021

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Purpose To update and extend the Carleton Laboratory for Radiotherapy Physics (CLRP) Eye Plaque (EP) dosimetry database for low‐energy photon‐emitting brachytherapy sources using egs_brachy, an open‐source EGSnrc application. The previous database, CLRP_EPv1, contained datasets for the Collaborative Ocular Melanoma Study (COMS) plaques (10–22 mm diameter) with 103Pd or 125I seeds (BrachyDose‐computed, 2008). The new database, CLRP_EPv2, consists of newly calculated three‐dimensional (3D) dose distributions for 17 plaques [eight COMS, five Eckert & Ziegler BEBIG, and four others representative of models used worldwide] for 103Pd, 125I, and 131Cs seeds. Acquisition and validation methods Plaque models are developed with egs_brachy, based on published/manufacturer dimensions and material data. The BEBIG plaques (modeled for the first time) are identical in dimensions to COMS plaques but differ in elemental composition and/or density. Previously benchmarked seed models are used. Eye plaques and seeds are simulated at the center of full‐scatter water phantoms, scoring in (0.05 cm)3 voxels spanning the eye for scenarios: (a) “HOMO”: simulated TG43 conditions; (b) “HETERO”: eye plaques and seeds fully modeled; (c) “HETsi” (BEBIG only): one seed is active at a time with other seed geometries present but not emitting photons (inactive); summation over all i seeds in a plaque then yields “HETsum” (includes interseed effects). For validation, doses are compared to those from CLRP_EPv1 and published data. Data format and access Data are available at https://physics.carleton.ca/clrp/eye_plaque_v2, http://doi.org/10.22215/clrp/EPv2. The data consist of 3D dose distributions (text‐based EGSnrc “3ddose” file format) and graphical presentations of the comparisons to previously published data. Potential applications The CLRP_EPv2 database provides accurate reference 3D dose distributions to advance ocular brachytherapy dose evaluations. The fully‐benchmarked eye plaque models will be freely distributed with egs_brachy, supporting adoption of model‐based dose evaluations as recommended by TG‐129, TG‐186, and TG‐221.

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“…The plaque's central axis (CAX) defines the

z

‐axis, with

x

and

y

Section: Acquisition and Validation Methodsmentioning

confidence: 99%

“…The egs++ class library geometry module is used to develop the eye plaque models: COMS plaques with diameters (

D

Section: Acquisition and Validation Methodsmentioning

confidence: 99%

Update of the CLRP eye plaque brachytherapy database for photon‐emitting sources

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The plaque's central axis (CAX) defines the z-axis, with x and y coordinates transverse to the plaque. Plaques contain between 5 and 33 seeds, with positions and orientations provided in the online CLRP EPv2 database based on earlier publications: TG-129 report 2 (COMS 10 -22 mm; BEBIG), Cutsinger et al 23 (COMS 24 mm), and Lespérance et al 14 (representative plaques: Cta, Sla, NlS, Ssa).…”

Section: Iia Monte Carlo Simulations Of Eye Plaquesmentioning

confidence: 99%

Update of the CLRP eye plaque brachytherapy database for photon-emitting sources

Safigholi¹,

Parsons²,

Deering³

et al. 2021

Update of the CLRP Eye Plaque Brachytherapy Database for Photon-Emitting Sources

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To update and extend the Carleton Laboratory for Radiotherapy Physics (CLRP) Eye Plaque (EP) dosimetry database for low-energy photon-emitting brachytherapy sources using egs brachy, an open-source EGSnrc application. The previous database, CLRP EPv1, contained datasets for the Collaborative Ocular Melanoma Study (COMS) plaques (10-22 mm diameter) with 103 Pd or 125 I seeds (BrachyDose-computed, 2008). The new database, CLRP EPv2, consists of newlycalculated 3D dose distributions for 17 plaques [8 COMS, 5 Eckert & Ziegler BEBIG, and 4 others representative of models used worldwide] for 103 Pd, 125 I, and 131 Cs seeds. Acquisition and Validation Methods: Plaque models are developed with egs brachy, based on published/manufacturer dimensions and material data. The BEBIG plaques (modelled for the first time) are identical in dimensions to COMS plaques but differ in elemental composition and/or density. Previously-benchmarked seed models are used. Eye plaques and seeds are simulated at the centre of fullscatter water phantoms, scoring in (0.05 cm) 3 voxels spanning the eye for scenarios: (i) 'HOMO': simulated TG43 conditions; (ii) 'HETERO': eye plaques and seeds fully modelled; (iii) 'HETsi' (BEBIG only): one seed is active at a time with other seed geometries present but not emitting photons (inactive); summation over all i seeds in a plaque then yields 'HETsum' (includes interseed effects). For validation, doses are compared to those from CLRP EPv1 and published data.

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“…The COMS 24 mm plaque was not a part of the original study and was developed by McCauley Custinger et al 56 for the Mayo Clinic in 2015. It was created to treat larger tumors than treatable by available COMS plaques.…”

Section: Eye Plaque Model Geometriesmentioning

confidence: 99%

Advanced Monte Carlo Dose Calculations for Eye Plaque Brachytherapy

Parsons¹

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Eye plaque brachytherapy is a radiation therapy technique designed for treating ocular cancers. Current clinical radiation dose evaluations for eye plaque brachytherapy involve considerable assumptions, resulting in inaccurate doses. This thesis aims to advance dose evaluations for eye plaque brachytherapy by implementation of detailed models for various photon and beta plaques in the egs_brachy Monte Carlo code. Calculated dose distributions are verified against published results. These plaque models and dose distributions will be distribued to the medical physics community. Dose distributions are calculated for differenct scenarios (clinical assumptions; plaque in water; plaque in realistic eye model). These results confirm the importance of model-based calculations for photon plaques and show that modelling tissues should be considered for beta plaques. Finally, dose distributions for photon and beta plaques are compared, demonstrating the potential of model-based dose evaluations in future studies. ii Without the support of my girlfriend, Hayley, my parents Chris and Cheryl, and my siblings Dustin, James, and Jesse, this thesis would never have taken shape. Thank you for always being there. I would like to thank my supervisor Dr. Rowan Thomson for her infinite patience and her advice in navigating the often bewildering currents of graduate research. I thank Stephen Deering and Marc Chamberland for laying the groundwork for the creation and use of eye plaque models in egs_brachy.Finally, my colleagues and friends among the Carleton Laboratory for Radiotherapy Physics deserve thanks:

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Seed coordinates of a new COMS‐like 24 mm plaque verified using the FARO Edge

Cited by 6 publications

References 4 publications

Update of the CLRP eye plaque brachytherapy database for photon‐emitting sources

Update of the CLRP eye plaque brachytherapy database for photon‐emitting sources

Update of the CLRP eye plaque brachytherapy database for photon-emitting sources

Advanced Monte Carlo Dose Calculations for Eye Plaque Brachytherapy

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