Sedentary behavior, physical inactivity and body composition in relation to idiopathic infertility among men and women

Foucaut, Aude-Marie; Faure, Céline; Julia, Chantal; Czernichow, Sébastien; Lévy, Rachel; Dupont, Charlotte

doi:10.1101/511030

Cited by 4 publications

(5 citation statements)

References 72 publications

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“…Results revealed that infertile women spend more time sitting (Mean = 274.6 ± 126.5 min/d) than fertile women (Mean = 225.3 ± 102.7 min/d), where females spending more than 5 hours a day sedentarily had more than twice the risk of being infertile (OR: 2.27, 95% CI 1.36–3.79). Congruent with our results, a recent case control study that was conducted on 159 infertile and 143 fertile men and women in France, provided that sedentary behaviour of women for more than 5 hours a day was associated with more than three times the risk (OR: 3.61, 95% CI, 1.58–8.25) [ 42 ]. It has been evidenced that aerobic exercise offers a remarkable effect on the follicular phase of ovulation and enhances the development of graafian follicles mainly among women suffering from Polycystic Ovary Syndrome (PCOs) [ 43 ], while sedentary life may expose females to increase risk of having PCOs [ 44 ].…”

Section: Discussionsupporting

confidence: 67%

The association of types, intensities and frequencies of physical activity with primary infertility among females in Gaza Strip, Palestine: A case-control study

Dhair

Abed

2020

PLoS ONE

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Introduction Physical activity and energy state balance have fundamentally been related to reproductive system and health. This study explored the relationship between different types, intensities and frequencies of physical activity with primary infertility among women in Gaza Strip, Palestine. Methods A case-control study was conducted in Gaza Strip with the participation of 320 married couples. 160 infertile couples were chosen from five fertility centers registries from 2016 to 2018 and matched residentially with 160 fertile couples. Cases were selected through systematic stratified sampling of five lists categorized according to residency and the determined percentage selected from each list was proportional. Data were collected through a self-administered questionnaire extended by the short form of international physical activity questionnaire and analyzed through SPSS program version 22 by using descriptive analysis, independent T-test, cross-tabulation, and binary logistic regression. Results Low frequency, intensity and duration of physical activity were associated with 3.1 risk of primary infertility (95% CI, 1.60–5.99, P < 0.001). Adjustment for age, marital age, age of menarche, refugee status and monthly income provided 3.2 risk (95% CI, 1.55–6.60, P = 0.002). Women spending more than 300 minutes a day sedentarily were 2.3 times more likely to have fertility problems than physically active females. Measuring energy expenditure in MET-min/w (Metabolic Equivalent) showed vigorous MET-min/w as negatively associated with the infertility status of females (Interquartile range IQR: 480 for cases and 720 for controls, P = 0.010). On the basis of energy expended in kilocalories in relation to weight, results showed the same association (IQR: 564 for case and 864 for controls, P = 0.011). No associations were found between moderate activity levels and primary infertility. Conclusion Low levels of physical activity and sedentary lifestyle endanger the fertility status of females in Gaza Strip. This may offer the need for endorsing and formalizing adequate physical activity education and awareness protocols in the national reproductive health guidelines and empowering environmental capacity building to alter physical activity-related cultural norms.

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Section: Discussionsupporting

confidence: 67%

The association of types, intensities and frequencies of physical activity with primary infertility among females in Gaza Strip, Palestine: A case-control study

Dhair

Abed

2020

PLoS ONE

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“…Recently, in a case-control study involving 302 men and women, we observed that physical inactivity was correlated with infertility in men [odds ratio (OR): 2.20; 95% CI: 1.06-4.58]. In this study, sedentary behaviour was also linked to female infertility (OR: 3.61; 95% CI: 1.58-8.24) [27].…”

Section: Physical Activitysupporting

confidence: 55%

“…Indeed, exposure to pollution, radiation, environmental toxicants, and endocrine disrupters is already known to impact fertility in both males and females [81]. Lifestyle factors such as addictions (tobacco, alcohol, drugs), inadequate diet, lack of physical activity, overweight, obesity, metabolic syndrome, inadequate sleep, and heightened stress levels may also compromise male and female fertility [2,3,27,30,31,81]. These lifestyle factors are of interest since they may be reversible and there is a possibility of acting on them.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of a therapeutic multiple-lifestyle intervention taking into account the periconceptional environment in the management of infertile couples: study design of a randomized controlled trial – the PEPCI study

Dupont

Aegerter

Foucaut

et al. 2020

BMC Pregnancy Childbirth

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Background: Infertility is defined as the inability to conceive after 12 months of unprotected intercourse. It affects approximately one in six couples seeking pregnancy in France or western countries. Many lifestyle factors of the couples' pre and peri-conceptional environment (weight, diet, alcohol, tobacco, coffee, drugs, physical activity, stress, sleep…) have been identified as risk factors for infertility in both males and females. The high prevalence rates of unhealthy diets and lifestyles in the reproductive population of industrialized countries are worrisome. Nevertheless, adoption of a healthy lifestyle may improve fertility but lifestyle changes are difficult to achieve and to maintain due notably to behavioral factors. Methods: Consequently, we decided to propose an interventional study aimed at improving the quality of life of infertile couples before the start of assisted reproductive technology treatment. It is a randomized controlled multicentre trial. Both members of the couples are involved in an integrated global care program (PEPCI for "Parcours Environnement PériConceptionnel en Infertilité") vs. usual care. This global intervention not only considers diet and/or physical activity but follows a holistic approach, including a multidisciplinary assessment to address complete physical, psychological and social well-being. According to patient needs, this includes interventions on weight, exercise, diet, alcohol and drugs, mental and social health.

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“…Sitting for more than 4 hours in this study may indicate a sedentary lifestyle or inadequate physical activity. According to Lalinde-Acevedo et al [ 28 ], physical activity improves semen qualities and this may be due to the fact that physically active men have lower fat mass compared to inactive men [ 29 ]. Increased fat mass in men reduces plasma testosterone levels and also increases gonadal temperatures due to increased fat tissue around the testes [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

Influence of Lifestyle and Environmental Factors on Semen Quality in Ghanaian Men

Blay

Pinamang

Sagoe

et al. 2020

International Journal of Reproductive Medicine

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Introduction. Male infertility is known to contribute about half of all infertility cases. In Ghana, the prevalence of male infertility is higher (15.8%) than in females (11.8%). Sperm quality is associated with the likelihood of pregnancy and known to be the cause of male fertility problems 90% of the time. Exposure to certain environmental factors reduces semen quality in men. The study examined the effects of environmental and lifestyle factors on semen quality in Ghanaian men. Materials and Methods. This was a cross-sectional study involving 80 apparent healthy adult males in their reproductive age. Participants were males referred to the laboratory (Immunology Unit of the Korle-Bu Teaching Hospital) for semen analysis test and/or culture and sensitivity. Participants were made to fill out a questionnaire which entailed selected environmental factors (accidents or trauma, exposure to chemicals, radiation, and heat) and lifestyle habits (including alcohol consumption, smoking, and whether participants sat more or less than 4 hours per day). Semen samples were then collected by masturbation into sterile containers and analysed in accordance with WHO guidance for semen analysis within 60 minutes after ejaculation and collection. Results. About 69% of participants had semen pH within the normal range compared to 15% whose pH were lower than 7.2. There was a significantly high number of immotile sperm cells ( p value = 0.017) in participants who sat for more than 4 hours as compared to those that sat for less than 4 hours in a day. Active sperm motility and viability showed significant increase ( p value = 0.002 and 0.009, respectively) in participants who kept their cell phones in their side pockets. Smoking produced a twofold decrease in sperm count as smokers had a significantly lower sperm count ( 12.28 ± 10.95 × 10 6 /ml) compared to the smoke-free ( 23.85 ± 22.14 × 10 6 /ml). For exposure to STDs, no significant differences were recorded among study groups concerning semen quality. Conclusion. Sperm quality in Ghanaian men is associated with lifestyle habits. Smoking and sitting for long hours influenced sperm motility and count, respectively. Knowledge of the factors that influence sperm quality in this geographical region can contribute to informed decisions on effective management of infertility in Ghanaian men.

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Sedentary behavior, physical inactivity and body composition in relation to idiopathic infertility among men and women

Cited by 4 publications

References 72 publications

The association of types, intensities and frequencies of physical activity with primary infertility among females in Gaza Strip, Palestine: A case-control study

The association of types, intensities and frequencies of physical activity with primary infertility among females in Gaza Strip, Palestine: A case-control study

Effectiveness of a therapeutic multiple-lifestyle intervention taking into account the periconceptional environment in the management of infertile couples: study design of a randomized controlled trial – the PEPCI study

Influence of Lifestyle and Environmental Factors on Semen Quality in Ghanaian Men

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