Sedative effect of acupuncture during cataract surgery

Gioia, Luigi; Cabrini, Luca; Gemma, Marco; Fiori, Rossana; Fasce, Francesco; Bolognesi, Gianluigi; Spinelli, Alessandra; Beretta, Luigi

doi:10.1016/j.jcrs.2006.06.027

Cited by 34 publications

(23 citation statements)

References 19 publications

(14 reference statements)

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“…Six studies measured heart rate before and after intervention; none of these reported a significant difference between the acupuncture and sham groups [10, 21–23, 25, 36]. Two studies also reported no significant difference in blood pressure [17, 23].…”

Section: Resultsmentioning

confidence: 99%

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Efficacy of Acupuncture in Reducing Preoperative Anxiety: A Meta‐Analysis

Bae

Min

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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Background. Acupuncture has been shown to reduce preoperative anxiety in several previous randomized controlled trials (RCTs). In order to assess the preoperative anxiolytic efficacy of acupuncture therapy, this study conducted a meta-analysis of an array of appropriate studies. Methods. Four electronic databases (MEDLINE, EMBASE, CENTRAL, and CINAHL) were searched up to February 2014. In the meta-analysis data were included from RCT studies in which groups receiving preoperative acupuncture treatment were compared with control groups receiving a placebo for anxiety. Results. Fourteen publications (N = 1,034) were included. Six publications, using the State-Trait Anxiety Inventory-State (STAI-S), reported that acupuncture interventions led to greater reductions in preoperative anxiety relative to sham acupuncture (mean difference = 5.63, P < .00001, 95% CI [4.14, 7.11]). Further eight publications, employing visual analogue scales (VAS), also indicated significant differences in preoperative anxiety amelioration between acupuncture and sham acupuncture (mean difference = 19.23, P < .00001, 95% CI [16.34, 22.12]). Conclusions. Acupuncture therapy aiming at reducing preoperative anxiety has a statistically significant effect relative to placebo or nontreatment conditions. Well-designed and rigorous studies that employ large sample sizes are necessary to corroborate this finding.

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Section: Resultsmentioning

confidence: 99%

“…Two other studies investigated discomfort according to VAS scale ratings (0–100 points) and reported that discomfort was higher in control groups (MD = −12.08, P < .00001, 95% CI [−14.2, − 10.13], Figure 6) [21, 22]. …”

Section: Resultsmentioning

confidence: 99%

Efficacy of Acupuncture in Reducing Preoperative Anxiety: A Meta‐Analysis

Bae

Min

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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“…Surprisingly, this simple search strategy yielded more trials than the updated review that used complex search strategies aimed at detecting all three groups in one trial. When trials published up to March 2008 were considered, we consequently included seven more acupuncture trials [41]–[47], two more acupoint stimulation trials [48], [49], and four more TENS trials [37], [50]–[52] than the previous review.…”

Section: Discussionmentioning

confidence: 99%

Three-Armed Trials Including Placebo and No-Treatment Groups May Be Subject to Publication Bias: Systematic Review

Koog¹,

We²,

Min

2011

PLoS ONE

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BackgroundIt has been argued that placebos may not have important clinical impacts in general. However, there is increasing evidence of a publication bias among trials published in journals. Therefore, we explored the potential for publication bias in randomized trials with active treatment, placebo, and no-treatment groups.MethodsThree-armed randomized trials of acupuncture, acupoint stimulation, and transcutaneous electrical stimulation were obtained from electronic databases. Effect sizes between treatment and placebo groups were calculated for treatment effect, and effect sizes between placebo and no-treatment groups were calculated for placebo effect. All data were then analyzed for publication bias.ResultsFor the treatment effect, small trials with fewer than 100 patients per arm showed more benefits than large trials with at least 100 patients per arm in acupuncture and acupoint stimulation. For the placebo effect, no differences were found between large and small trials. Further analyses showed that the treatment effect in acupuncture and acupoint stimulation may be subject to publication bias because study design and any known factors of heterogeneity were not associated with the small study effects. In the simulation, the magnitude of the placebo effect was smaller than that calculated after considering publication bias.ConclusionsRandomized three-armed trials, which are necessary for estimating the placebo effect, may be subject to publication bias. If the magnitude of the placebo effect is assessed in an intervention, the potential for publication bias should be investigated using data related to the treatment effect.

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“…Relying on traditional point locations to differentiate the exposures resulted in statistically significant differences in four studies [35,44,80,82] but not in studies of migraine [48], chemotherapy induced nausea [54], knee osteoarthritis [61], or for emotional distress or cravings among substance users [69]. Relying on traditional indications of acupuncture points to differentiate the exposures resulted in statistically significant differences in one study [15], but not in studies of migraine [8,19], depression [9], low back pain [13], cataract surgery [23], nausea and vomiting during cesarean [25], or during early pregnancy [27], nor for diabetic peripheral neuritis [37]. Relying on stimulation techniques to differentiate the exposures resulted in statistically significant differences in two studies [53,81], but deep vs. minimal needle insertion led to no statistically significant differences in reduction in migraine [8,19,48], low back pain [13], pregnant women's pelvic pain [51], or knee osteoarthritis [61]; nor did needling compared to moxibustion have a statistically significant difference on outcomes for pain or ''coldness'' [64].…”

Section: Acupuncture Controlsmentioning

confidence: 99%

“…Among 40 studies that compared acupuncture exposures, 21 observed null outcomes and 18 of these (86%) had exposures that relied on traditional acupuncture theories of point locations [38,41,48,52,54,61,69], indications [8,9,13,19,23,25,27,37], or stimulation [8,13,16,19,48,51,61,64].…”

Section: Acupuncture Controlsmentioning

confidence: 99%