Sédation par kétamine en prévention de la douleur liée aux gestes invasifs en oncologie pédiatrique

Ricard, C.; Tichit, R.; Troncin, R.; Bernard, Francis

doi:10.1684/bdc.2009.0890

Cited by 4 publications

(2 citation statements)

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“…Thus, IV ketamine doses (50 µg/kg top-ups every 4-5 min) following the first 250 µg/kg bolus plus propofol 10-20 mg/70 kg boluses, are suitable in these cases. Vital signs monitoring includes HR and SpO 2 ; post-procedural monitoring and nursing surveillance are necessary, in order to tackle potential respiratory, hemodynamic, or cognition changes [138], until full coherence is regained [186]. The present authors detected no remarkable AEs in > 6000 out of OR ketamine-administered cases.…”

Section: Procedures Out Of the Or (Ed Excluded) Mostly In Childrenmentioning

confidence: 61%

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Role and Advantageousness of Ketamine in Obese and Non-Obese Patients: Peri-Interventional Considerations

Amit

2018

JPT

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Obese and morbidly obese patients are a growing group of individuals that generates medical, social and economicproblems worldwide. They undergo various interventions that require anesthesia and/or analgesia. Despite theirhealthy look, these individuals are graded at high ASA physical status, mainly because of their impaired respiratoryand cardiovascular conditions, and the metabolic changes their body undergoes. Opioids are the default drugsfor perioperative analgesia. Nevertheless, their use has reached a frightening epidemic-like condition worldwide.Multimodal analgesia regimens have been recommended as a perioperative standard of care, particularly useful in theobese. These regimens employ combinations of opioids and non-opioid compounds that reciprocate each analgesicpotencies, thus providing superior pain relief at rest, movement, or on effort, while reducing opioid consumption andtheir concerned adverse effects. The most important perioperative IV adjuvant currently employed is ketamine thatsees resurgence among physicians from diverse medical specialties. After summarizing obese patients’ perioperativedrawbacks, this review will illustrate ketamine’s neuropharmacology, and will describe its therapeutic usefulness asan analgesic adjuvant. Since data regarding the use of the drug in obese patients is scarce, brief exemplifications ofits benefits in non-obese cohorts will be portrayed as well.

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Section: Procedures Out Of the Or (Ed Excluded) Mostly In Childrenmentioning

confidence: 61%

“…[230]. The presence of ketamine provided obvious superior periinterventional effects [186], as judged by ratings by both treatees and care givers. From the neuropharmacological and clinical aspects, ketamine is a better choice than dexmedetomidine, mainly since it provides stable hemodynamic conditions.…”

Section: Inhalational Ketamine: Ketamine By Inhalationmentioning

confidence: 97%