Sedation in the Intensive Care Unit

Abstract

Considering the widespread use of sedation for critically ill patients, more large, high-quality, randomized controlled trials of the effectiveness of different agents for short-term and long-term sedation are warranted.

SEDLine Monitored Sedation and Recovery for Postoperative Ventilated Recipients of Living Donor Liver Transplantation: A Randomized Controlled Trial

“…There is evidence in literature that increased sedation is associated with higher risk of postoperative complications [18]. Cost has become a matter of increasing concern, in our current study we reported higher costs in R group compared to S group and this could be due to the less hospital stay and sedative used [19]. This study provide support that the-sedline (PSI)-augmented sedation has an advantageous effects on recovery, ventilation, hemodynamics, hospital stay, inhalational requirements, cost and postoperative complications when compared with Ramsay monitored sedation.…”

Effects of early rehabilitation therapy on patients with mechanical ventilation

“…sedation was associated with the prolongation of mechanical ventilation in the ICU. [25,26] Daily interruption of sedation in critically ill patients with mechanical ventilation can result in a decreased duration of mechanical ventilation and a decreased length of ICU stay. [27] Deep sedation and immobility might potentiate ICU-acquired neuromuscular weakness.…”

Sedation And Analgesia After Cardiac Surgery: Comparison Of Dexmedetomidine, Midazolam /Fentanyl And Midazolam/Dexketoprofen Trometamol

“…Çoğu hastanın mekanik ventilasyonu tolere edebilmesi ve hemodinamik stabiliteyi sağlayabilmesi için sedasyon ve analjezi gereklidir [5] . Yoğun bakımda sedasyonun amacı hastaların konforlu, sakin ve ağ-rısız kalmalarını sağlamaktır.…”