Securing epidural catheters with Histoacryl^® glue

A 4-arm randomized controlled pilot trial of innovative solutions for jugular central venous access device securement in 221 cardiac surgical patients

“…TA use has been favourably assessed for CVADs in case studies [19,20], and even implemented as routine in at least one hospital [18]. Ours is the first RCT to assess TA for CVAD securement, and we found it was ineffective with SPU alone, but was effective when combined with suturing and an SPU.…”

“…In short peripheral arterial and venous lines, TA securement led to absolute reductions in catheter failure ranging from 11% to 24% compared to traditional non-bordered polyurethane films [14][15][16]. We hypothesised that TA could also improve CVAD securement, although only case-series have to date reported its use for this indication with mixed results [17][18][19][20].…”

Current Epidural Practice – Results of a Survey of Military Anaesthetists

“…This may be of particular significance for the military patient population where patients may present having been contaminated by significant amounts of dirt and dust. Glue can also be used to prevent accidental removal [10] and this survey has also highlighted the fact that very few responders use this as part of their routine UK practice. As with tunnelling the use of glue to reduce the chance of catheter displacement is of particular relevance on deployment where patients who have epidural catheters inserted in the Field Hospital may have them running all through their repatriation (with all the moving and handling this entails) and on into their management in the UK.…”

2-Octyl Cyanoacrylate Adhesive for the Prevention of Central Venous Catheter Infections: A Proof of Concept

“…Since approval by the FDA in 1998 for the clinical use of 2-octyl cyanoacrylate as a topical skin adhesive there has been widespread adoption of this product in the care of surgical and trauma patients for wound closure [8] with subsequent proven efficacy in decreasing surgical site infections in vivo when used on surgical wounds [6,[9][10][11]. Additionally, An in vitro study from Simonova et al [6] showed no bacterial growth under 16 GA 1.16" (1.7x30 mm) Insyte ™ Autoguard ™ (BD, Franklin Lakes, NJ, USA) Intravascular catheters applied with tissue adhesive [6].…”

“…Additionally, An in vitro study from Simonova et al [6] showed no bacterial growth under 16 GA 1.16" (1.7x30 mm) Insyte ™ Autoguard ™ (BD, Franklin Lakes, NJ, USA) Intravascular catheters applied with tissue adhesive [6]. While 2-octyl cyanoacrylate is not FDA approved for the use of securing CVCs, the off-label use of a tissue adhesive for securement of CVCs was first reported in 2007 in 30 burn patients [7] with the same group reporting successful use of this adhesive for securing 50 thoracic epidural catheters [11]. We investigated the utilization of this product for the securement of CVCs off-label.…”