Secular trends in acute dialysis after elective major surgery — 1995 to 2009

Siddiqui, Nausheen; Coca, Steven G.; Devereaux, P. J.; Jain, Arsh K.; Li, Lihua; Luo, Jin; Parikh, Chirag R.; Paterson, Michael; Thiessen-Philbrook, Heather; Wald, Ron; Walsh, Michael; Whitlock, Richard; Garg, Amit X.

doi:10.1503/cmaj.110895

Cited by 117 publications

(118 citation statements)

References 37 publications

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“…The second case report presented above demonstrated the syndrome of rapid onset ESRD, or SORO-ESRD, that is to say, acute yet irreversible renal failure requiring permanent RRT including kidney transplantation where applicable (7)(8)(9)(10). Several other large studies of the trajectories of renal failure to ESRD have confirmed our observations (18)(19)(20). In the more recent nephrology literature, 2011-2012, we have further identified three corroborating new reports that have further substantiated our recent descriptions of the phenomenon of SORO-ESRD (18)(19)(20).…”

Section: Discussionsupporting

confidence: 89%

“…Several other large studies of the trajectories of renal failure to ESRD have confirmed our observations (18)(19)(20). In the more recent nephrology literature, 2011-2012, we have further identified three corroborating new reports that have further substantiated our recent descriptions of the phenomenon of SORO-ESRD (18)(19)(20). These three reports have each additionally demonstrated that a significant proportion of the incident adult ESRD population in both the United States and Canada, respectively, satisfy the diagnostic criteria for our newly described syndrome of rapid onset end stage renal disease (18)(19)(20).…”

Section: Discussionsupporting

confidence: 87%

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Late onset renal failure from angiotensin blockade (LORFFAB) and the syndrome of rapid onset endstage renal disease (SORO-ESRD) revisited – Two case reports from Mayo Clinic Health System, Northwestern Wisconsin, USA; a review paper

Onuigbo¹,

Samuel²,

Agbasi³

2018

J Renal Inj Prev

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In 2005, we had described for the first time, the syndrome of late onset renal failure from angiotensin blockade (LORFFAB), represented by the observed accelerated loss of kidney function in patients on a priori stable doses of an angiotensin converting enzyme inhibitor and/or an angiotensin receptor blocker, for more than three months, with this acute kidney injury (AKI) occurring despite the absence of any identifiable known precipitating factors. Moreover, in 2010, we had described the syndrome of rapid onset end-stage renal disease (SORO-ESRD), represented by acute yet irreversible renal failure following medical illness or surgical procedures, again sometimes in association with concurrent angiotensin blockade. In this article, we describe two representative case reports, one each of both syndromes, and discuss the implications of LORFFAB and SORO-ESRD in current nephrology practice paradigms.Please cite this paper as: Onuigbo M, Samuel E, Agbasi N. Late onset renal failure from angiotensin blockade (LORFFAB) and the syndrome of rapid onset end-stage renal disease (SORO-ESRD) revisited -Two case reports from Mayo Clinic Health System, Northwestern Wisconsin, USA; a review paper. J Renal Inj Prev. 2018;7(2):58-63. DOI: 10.15171/jrip.2018.15. In 2005, we described for the first time, the syndrome of late onset renal failure from angiotensin blockade (LORFFAB). This is accelerated loss of kidney function in patients on a priori stable doses of an angiotensin converting enzyme inhibitor and/or an angiotensin receptor blocker (ARB), for more than 3 months, with this acute kidney injury (AKI) occurring in the absence of any identifiable known precipitating factors. Moreover, in 2010, we described the syndrome of rapid onset end-stage renal disease (SORO-ESRD). This is acute yet irreversible renal failure following medical illness or surgical procedures, again sometimes in association with concurrent angiotensin blockade. In this article, we describe two representative case reports, one case for LORFFAB and another case for SORO-ESRD and subsequently discuss the implications of LORFFAB and SORO-ESRD in current nephrology practice paradigms. Whereas we support the consensus that angiotensin blockade, for now, remains the mainstay of renoprotection, we however must draw attention to the potential for nephrotoxicity from angiotensin blockade under certain clinical scenarios including the ones described here and more. The association of LORFFAB and SORO-ESRD demands further investigation.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 87%

Late onset renal failure from angiotensin blockade (LORFFAB) and the syndrome of rapid onset endstage renal disease (SORO-ESRD) revisited – Two case reports from Mayo Clinic Health System, Northwestern Wisconsin, USA; a review paper

Onuigbo¹,

Samuel²,

Agbasi³

2018

J Renal Inj Prev

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“…The median number of pregnancies per mother during the study period was 1 (interquartile range [IQR] 1-2; range 1-11). The median maternal age at delivery was 30 years (IQR [26][27][28][29][30][31][32][33][34]. The prevalence of at least one recorded preexisting medical condition, including hypertension, diabetes mellitus, or chronic kidney disease, was 5.3%.…”

Section: Pregnancies In Ontario Canadamentioning

confidence: 99%

“…25 Maternal cause of death was determined from the Ontario Registrar General Death database, which contains information on all deaths registered in Ontario. 26 We have used these databases in previous studies to research health outcomes and health services including those related to AKI-D. [29][30][31][32] All variables used in this study were complete, with minor exceptions detailed in Supplemental Table 3.…”

Section: Data Sourcesmentioning

confidence: 99%

Characteristics and Outcomes of AKI Treated with Dialysis during Pregnancy and the Postpartum Period

Hildebrand

Liu

Shariff

et al. 2015

Journal of the American Society of Nephrology

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Acute kidney injury (AKI) is a rare complication of pregnancy, but may be associated with significant morbidity and mortality in young and often otherwise healthy women. We conducted a retrospective population-based cohort study of all consecutive pregnancies over a 15-year period (1997-2011) in Ontario, Canada, and describe the incidence and outcomes of AKI treated with dialysis during pregnancy or within 12 weeks of delivery. Of 1,918,789 pregnancies, 188 were complicated by AKI treated with dialysis (incidence: 1 per 10,000 [95% confidence interval, 0.8 to 1.1]). Only 21 of 188 (11.2%) women had record of a preexisting medical condition; however, 130 (69.2%) women experienced a major pregnancy-related complication, including preeclampsia, thrombotic microangiopathy, heart failure, sepsis, or postpartum hemorrhage. Eight women died (4.3% versus 0.01% in the general population), and seven (3.9%) women remained dialysis dependent 4 months after delivery. Low birth weight (,2500 g), small for gestational age, or preterm birth (,37 weeks' gestation) were more common in pregnancies in which dialysis was initiated (35.6% versus 14.0%; relative risk, 3.40; 95% confidence interval, 2.52 to 4.58). There were no stillbirths and fewer than five neonatal deaths (,2.7%) in affected pregnancies compared with 0.1% and 0.8%, respectively, in the general population. In conclusion, AKI treated with dialysis during pregnancy is rare and typically occurs in healthy women who acquire a major pregnancy-related medical condition such as preeclampsia. Many affected women and their babies have good short-term outcomes. 26: 3085-3091, 201526: 3085-3091, . doi: 10.1681 Pregnancy-related AKI is associated with significant morbidity and mortality inyoung and often otherwise healthy women. 1,2 Since the 1960s, the incidence of pregnancy-related AKI in developed countries has declined from 1 in 3000 to 1 in 18,000. 1 This trend has been closely linked to improved obstetrical care and dramatic reductions in first-trimester AKI attributable to septic abortions. 2 However, these trends are less relevant in contemporary populations. The changing risk profile of pregnant North American women includes lower parity, older age, higher body mass index, and greater comorbidities such as hypertension, diabetes mellitus, and chronic kidney disease, as well as increased use of reproductive technologies resulting in multiple gestations. These changes may have a unique impact on the incidence, etiology, and outcomes of pregnancy-related AKI. [3][4][5][6][7] J Am Soc Nephrol

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“…Indeed, the overarching trend over time seems to be toward earlier and more continuous dialysis (22). This question speaks to a misunderstood risk-benefit calculus.…”

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confidence: 99%

A Policy of Preemption

Wilson¹

2014

Clinical Journal of the American Society of Nephrology

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Secular trends in acute dialysis after elective major surgery — 1995 to 2009

Cited by 117 publications

References 37 publications

Late onset renal failure from angiotensin blockade (LORFFAB) and the syndrome of rapid onset endstage renal disease (SORO-ESRD) revisited – Two case reports from Mayo Clinic Health System, Northwestern Wisconsin, USA; a review paper

Late onset renal failure from angiotensin blockade (LORFFAB) and the syndrome of rapid onset endstage renal disease (SORO-ESRD) revisited – Two case reports from Mayo Clinic Health System, Northwestern Wisconsin, USA; a review paper

Characteristics and Outcomes of AKI Treated with Dialysis during Pregnancy and the Postpartum Period

A Policy of Preemption

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