Secular trend in the sexual maturation of Southern Chinese girls

Huen, K. F.; Leung, S. S. F.; Lau, Joseph T. F.; Cheung, Albert Y.; Leung, Nwy; Chiu, Mc

doi:10.1111/j.1651-2227.1997.tb14820.x

Cited by 120 publications

(68 citation statements)

References 10 publications

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“…They found that the time pattern of sexual maturation was comparable to that of Europeans, with the exception that Asians developed pubic hair later. Huen et al (Huen et al, 1997) published a similar study including 3,749 girls from southern China. They found that, according to the mean values for the individual stages of maturity, the examined girls were among the earliest to reach sexual maturity worldwide.…”

Section: Sexual Maturationmentioning

confidence: 80%

“…Comparative studies on sexual maturation were conducted by Harlan et al (Harlan et al, 1979(Harlan et al, , 1980, Channing-Pearce and Solomon (Channing-Pearce & Solomon, 1987), Wong et al (Wong et al, 1996) and Huen et al (Huen et al, 1997). Between 1966, Harlan et al (Harlan et al, 1979 analysed the sexual development of 6,768 male Americans aged between 12 and 17 years.…”

Section: Sexual Maturationmentioning

confidence: 99%

See 1 more Smart Citation

Forensic Age Estimation in Unaccompanied Minors and Young Living Adults

Schmeling¹,

Garamendi²,

Prieto³

et al. 2011

Forensic Medicine - From Old Problems to New Challenges

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Section: Sexual Maturationmentioning

confidence: 80%

Section: Sexual Maturationmentioning

confidence: 99%

Forensic Age Estimation in Unaccompanied Minors and Young Living Adults

Schmeling¹,

Garamendi²,

Prieto³

et al. 2011

Forensic Medicine - From Old Problems to New Challenges

View full text Add to dashboard Cite

“…Firstly, although puberty may affect IGFBP-3 or IGF-I concentrations, 14 the pubertal state of the participants was not assessed in this study due to the practical difficulties of doing so in such a large cohort. Nonetheless, given that the median age of puberty in Hong Kong is 11.4 years and 9.8 years in boys and girls, respectively, 40,41 the majority of our participants (mean age of 15.3 + 2.0 and 15.7 + 2.0 years in boys and girls, respectively) were post-pubertal. Secondly, apart from …”

Section: Discussionmentioning

confidence: 99%

Serum concentrations of insulin-like growth factor-I, insulin-like growth factor binding protein-3 and cardiovascular risk factors in adolescents

Kong¹,

Choi²,

Wong³

et al. 2011

Ann Clin Biochem

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Background: The risk association between the insulin like growth factor-I (IGF-I) system and cardiovascular risk is inconclusive in adults and under-explored in adolescents. We aimed to investigate the associations between serum concentrations of IGF-I and IGF binding protein-3 (IGFBP-3) and cardiovascular risk factors in adolescents.Methods: This was a cross-sectional, population-based, observational study in a school setting with 2102 Hong Kong Chinese adolescents aged 12-19 years. Serum IGF-I and IGFBP-3 concentrations were measured by chemiluminescence immunoassays. Anthropometric indices and traditional cardiovascular risk factors were assessed. Results: After excluding participants with abnormal thyroid and liver test results, 765 boys and 877 girls, mean (+SD) age of 15.3 (+2.0) and 15.7 (+2.0) years, respectively, were included in the analysis. Multivariable regression analyses revealed that both IGF-I and IGFBP-3 concentrations were independently associated with waist circumference, fasting insulin and haemoglobin concentrations in boys (all P , 0.05), systolic blood pressure, serum creatinine, fasting insulin and haemoglobin concentrations in girls (all P , 0.05). In girls, IGF-I was also associated with C-reactive protein concentration (P , 0.001) and IGFBP-3 was associated with fasting triglyceride concentration (P , 0.001). Compared with adolescents with the lowest tertile, the top tertile of both IGF-I and IGFBP-3 concentrations were associated with increased odds of having overweight/ obesity, top tertiles of insulin and haemoglobin in both boys and girls (P for trend, all ,0.05). Conclusions:The associations between serum IGF-I, IGFBP-3, obesity, cardiovascular risk factors, insulin and haemoglobin suggest that dysregulation of the IGF system may play a linking role for the clustering of cardiovascular risk factors.

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“…40 This frequency of assessment provides reliable measurements of pubertal development, which are similar to the references for normal pubertal development in Chinese boys and girls in Hong Kong. 41,42 Children with infeasible sequences of pubertal stages, such as Tanner stage II before stage I, were excluded (n = 87).…”

Section: Exposuresmentioning

confidence: 99%

Age at Onset of Puberty and Adolescent Depression: “Children of 1997” Birth Cohort

et al. 2016

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OBJECTIVE: Timing of onset of puberty has fallen, with profound and detrimental consequences for health. We examined the associations of earlier onset of puberty with the presence of depression in early to middle adolescence. METHODS:The study examined prospective adjusted associations of age at onset of puberty, based on clinically assessed Tanner stage for breast/genitalia and pubic hair development, and self-reported presence of depression, assessed from the 9-item Patient Health Questionnaire on average at 13.6 years (n = 5795 [73%]). These factors were examined by using multivariable logistic regression in a population-representative Hong Kong Chinese birth cohort (ie, the "Children of 1997"). We also assessed whether associations varied according to gender. RESULTS:Association of age at onset of breast/genitalia development with the presence of depression varied according to gender. Earlier onset of breast development was associated with higher risk of the presence of depression (odds ratio, 0.83 per 1 year increase in age of onset [95% confidence interval, 0.70 to 0.98]) adjusted for age, socioeconomic position, mother's place of birth, birth order, secondhand smoke exposure, parental age, survey mode, gender-specific birth weight z score, BMI z score at 7 years, and parental marital status. In boys, similarly adjusted, age at onset of genitalia development was unrelated to the presence of depression. Earlier age at onset of pubic hair development was unrelated to the presence of depression in girls and boys.CONCLUSIONS: Early onset of breast development was associated with high risk of the presence of depression. Whether these findings are indicators of the effects of hormones or transient effects of social pressures remain to be determined.

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Secular trend in the sexual maturation of Southern Chinese girls

Cited by 120 publications

References 10 publications

Forensic Age Estimation in Unaccompanied Minors and Young Living Adults

Forensic Age Estimation in Unaccompanied Minors and Young Living Adults

Serum concentrations of insulin-like growth factor-I, insulin-like growth factor binding protein-3 and cardiovascular risk factors in adolescents

Age at Onset of Puberty and Adolescent Depression: “Children of 1997” Birth Cohort

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