Secular increase and geographical differences in hip fracture incidence in Norway

Falch, Jan A.; Kaastad, T S; Böhler, G.; Espeland, J.; Sundsvold, O.-J.

doi:10.1016/8756-3282(93)90086-p

Cited by 115 publications

(63 citation statements)

References 9 publications

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“…The healthy children were randomly chosen from the population and individually matched with the patients according to age, sex, ethnicity, and geography. The geographic match may reduce a bias caused by geographic differences in femoral neck geometry, BMD, and fracture rates related to environmental factors or genetic risk determinants (29,30).…”

Section: Discussionmentioning

confidence: 99%

A two‐year prospective controlled study of bone mass and bone turnover in children with early juvenile idiopathic arthritis

Lien¹,

Selvaag²,

Flatø³

et al. 2005

Arthritis & Rheumatism

103

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Objective. To explore early changes and predictors of bone mass in children with juvenile idiopathic arthritis (JIA) in order to identify patients who will develop bone mass reductions.Methods. We conducted a prospective cohort study of 108 children with early JIA (ages 6-18 years; mean disease duration 19.3 months) who were individually matched with 108 healthy children for age, sex, race, and county of residence. Bone mass and changes in total body, spine, femur, and forearm bone mineral density and bone mineral content (BMC), body composition, growth, and biochemical parameters of bone turnover were examined at baseline and at followup a mean of 24 months later. Low bone mass was defined as a Z score >1 SD below the reference population.Results. Of the 200 children evaluated at followup, the 100 healthy children had greater gains in total body BMC (P ‫؍‬ 0.035), distal radius BMC (P < 0.001), and total body lean mass (P < 0.001) than did the 100 JIA patients. Low or very low total body BMC was observed in 24% of the patients and 12% of the healthy children. Bone formation, bone resorption, and weight-bearing activities were reduced in the patients compared with the healthy children. Multiple regression analysis showed that in patients with JIA, serum bonespecific alkaline phosphatase, serum C-telopeptide of type I collagen, and weight-bearing activities were independent predictors of changes in total body BMC. Total body BMC was lower in patients with polyarticular onset than in those with oligoarticular disease onset.Conclusion. Patients with JIA have moderate reductions in bone mass gains, bone turnover, and total body lean mass early in the disease course.

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Section: Discussionmentioning

confidence: 99%

A two‐year prospective controlled study of bone mass and bone turnover in children with early juvenile idiopathic arthritis

Lien¹,

Selvaag²,

Flatø³

et al. 2005

Arthritis & Rheumatism

103

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“…The previously estimated number of hip fractures among adults in Norway, i.e. 9,000) [1], has been verified using data from NORHip [5], and the previously reported differences in hip fracture rates between Norwegian counties [6,47], are still present.…”

Section: Forearm Fracturementioning

confidence: 65%

Cohort profile: Norwegian Epidemiologic Osteoporosis Studies (NOREPOS)

Søgaard

Meyer

Emaus

et al. 2014

Scand J Public Health

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AimsThis paper describes the history, purpose, data collection and contributions in the research collaboration Norwegian Osteoporosis Epidemiologic Studies (NOREPOS). Methods NOREPOS encompasses almost ResultsMain findings include: Every hour a Norwegian suffers a hip fracture; hip fracture incidence rates declined after 1999; only 16% of patients used anti-osteoporosis drugs one year after hip fracture; 25% of patients died within one year after the fracture; 12% suffered a new hip fracture within 10 years; rural dwellers had lower hip-and forearm fracture incidence than city dwellers; magnesium in tap water may be protective whereas bacterial contamination, cadmium and lead may be harmful to bone health; low serum vitamin D and E levels were associated with higher hip fracture risk; vitamin A was not associated with fracture risk; and abdominal obesity increased the risk of hip fracture when BMI was accounted for. Conclusion

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“…9000 operasjoner og innleggelser som følge av hoftebrudd. Tidligere studier har vist at insidensen av hoftebrudd i Norge er blant de høyeste i verden (1,2). Insidensen av hoftebrudd øker eksponensielt med økende alder (2,3).…”

Section: Bakgrunnunclassified

The Norwegian Hip Fracture Register / Nasjonalt Hoftebruddregister

Gjertsen¹,

Fevang²,

Vinje³

et al. 2009

Nor J Epidemiol

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SAMMENDRAGBakgrunn: Hvert år opereres det i Norge ca. 9000 pasienter for hoftebrudd. Hoftebrudd er en diagnose assosiert med høy mortalitet og morbiditet. Det er ingen konsensus i Norge om hvordan hoftebrudd, og spesielt de dislokerte lårhalsbruddene, skal opereres. Nasjonalt Hoftebruddregister ble 01.01.05 opprettet ved Nasjonalt Kompetansesenter for Leddproteser for å kvalitetssikre behandlingen av pasienter med hoftebrudd. Materiale og metode: Det er opprettet kontaktpersoner til registeret ved alle sykehus hvor det opereres hoftebrudd. Etter hver operasjon fyller operatør ut et operasjonsskjema som sendes til registeret. I tillegg til pasientdata og opplysninger om operasjonen som er utført, blir alle implantater registrert så nøyaktig som mulig, helst ved hjelp av katalognummer. Et oppfølgingsskjema sendes til alle registrerte pasienter 4 og 12 måneder etter primaeroperasjonen. Dette skjemaet består blant annet av den norske utgaven av EuroQol-5D. Resultater: Etter 1 års registrering har vi 100% oppslutning fra sykehusene og 51% svarprosent på pasientspørreskjema. Vi har inkludert 5668 primaeropererte pasienter (gjennomsnittsalder 80,3 år og 72,5% kvinner) og har registrert 500 reoperasjoner. Diskusjon: Databasen vil kunne kobles opp mot andre registre som for eksempel hofteproteseregisteret og vil kunne bidra til økt kunnskap om hoftebruddpasientene. Vi vil undersøke overlevelse av implantater og pasienter samt funksjonsnivå hos pasienter etter ulike behandlingsmetoder. Databasen fungerer tilfredsstillende og vi regner med flere publikasjoner i løpet av de første årene. ENGLISH SUMMARYBackground: Every year 9000 patients in Norway are operated due to hip fractures. A hip fracture is a diagnosis associated with high mortality and morbidity. The patient population is increasing and large resources are used in the treatment of these patients. There is no consensus in Norway stating the preferred method of treatment. The Norwegian Hip Fracture Register was founded at the National Arthroplasty Register 1. January 2005. Material and methods:We have established contacts at every hospital in Norway that perform surgery for hip fractures. After surgery, the surgeon fills in a standardized form, which is sent to the register once a month. On the form there are both patient-and procedure-related questions. To ensure accurate information on the implants, the surgeons use stickers with catalogue numbers supplied by the manufacturers. After four and twelve months a questionnaire is sent to each patient. Among other questions we used the Norwegian translation of the EuroQol-5D (EQ-5D) which is a non-disease-specific instrument for describing and valuing health-related quality of life.All the results are stored in our database. The information is linked to the Norwegian Registry of Vital Statistics by use of the unique identification number assigned for each resident of Norway. Results: After one year of registration 100% of the hospitals are reporting to the register. 51% of the patients have answered the questionnaire....

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Secular increase and geographical differences in hip fracture incidence in Norway

Cited by 115 publications

References 9 publications

A two‐year prospective controlled study of bone mass and bone turnover in children with early juvenile idiopathic arthritis

A two‐year prospective controlled study of bone mass and bone turnover in children with early juvenile idiopathic arthritis

Cohort profile: Norwegian Epidemiologic Osteoporosis Studies (NOREPOS)

The Norwegian Hip Fracture Register / Nasjonalt Hoftebruddregister

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