Section IV. Radiation Therapy of Glomus Jugulare Tumors

Carrasco, Vincent N.; Rosenman, Julian G.

doi:10.1002/lary.1993.103.s60.23

Cited by 56 publications

(23 citation statements)

References 31 publications

(9 reference statements)

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“…The therapeutic options for GJT treatment include surgery, radiotherapy and embolization, which can be used combined or individually. [1234567891023242526272829] Their management should also take into account two important aspects. The first is that most patients have benign, very slow-growing tumors, although malignancy can occur infrequently.…”

Section: Discussionmentioning

confidence: 99%

Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors

Andrade¹,

Brito²,

Mario³

et al. 2013

Surg Neurol Int

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Background:The glomus jugulare tumor is a slowly growing benign neoplasm originating from neural crest. There is a high morbidity associated with surgical resection of glomus jugulare. Radiosurgery play a relevant role as a therapeutic option in these tumors and its use has grown in popularity. The authors describe a retrospective series of 15 patients and reviewed the literature about the glomus jugulare tumors.Methods:We reviewed retrospectively the data of 15 patients treated with stereotactic linear accelerator stereotactic radiosurgery (LINAC) radiosurgery between 2006 and 2011.Results:The average tumor volume was 18.5 cm3. The radiation dose to the tumor margin ranged between 12 and 20 Gy. The neurological status improved in three patients and remained unchanged in 12 patients. One patient developed a transient 7th nerve palsy that improved after clinical treatment. All tumors remained stable in size on follow-up with resonance magnetic images.Conclusions:The radiosurgery is a safe and effective therapy for patients with glomus jugulare tumor. Despite the short follow-up period and the limited number of patients analyzed, we can infer that radiosurgery produce a tumor growth control with low morbidity, and may be used as a good option to surgical resection in selected cases.

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Section: Discussionmentioning

confidence: 99%

Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors

Andrade¹,

Brito²,

Mario³

et al. 2013

Surg Neurol Int

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“…This may explain the long-term consistency of LTC rates (8,35,37). The incidence of complications is relatively low (0-10%), but the quality of these sequelae may go from focal parenchymal radionecrosis of the brain to osteonecrosis of the temporal bone, mastoiditis, mucositis, alopecia, and uncontrolled tumor regrowth (3,(7)(8)(9)15). A radiation-induced case of malignant evolution has been reported (23).…”

Section: Fractionated Radiation Therapymentioning

confidence: 98%

Glomus Jugulare Tumors

et al. 2006

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“…Radiation has generally been recommended as a primary treatment only for poor surgical candidates, such as elderly patients, those with extensive skull-base involvement, and those with significant secondary health concerns (1,7,8,9,13). There are now many studies demonstrating that rates of local control (defined as stabilization or regression of tumor size and lack of progression of neurologic symptoms) may be as good as or better than surgery (8,9).…”

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confidence: 98%

“…The treatment of the glomus jugulare tumor can be particularly difficult because of its origin in the jugular bulb, a location that may lead to involvement of the middle ear, lower cranial nerves, the jugular vein, carotid artery, and intracranial structures. However, the optimal form of therapy for this tumor is highly controversial (1)(2)(3)(4)(5)(6)(7). There are no randomized controlled trials comparing the efficacy of current treatments, which include surgical resection, fractionated beam radiation, embolization and, more recently, gamma knife radiosurgery.…”

mentioning

confidence: 99%