Secretory carcinoma of the breast in a 20-year-old male: Case report and review of literature

Abstract

Secretory breast carcinoma (SBC) is a very rare low-grade subtype of breast carcinoma. It was initially termed “juvenile breast cancer,” but it is now known to occur in adults of both sexes, and only few male cases have been reported in the literature. SBC is of importance because of its unique morphology and excellent prognosis. We report here a case in a 20-year-old male presenting with right pedunculated and ulcerated breast mass with associated contact bleeding. Histopathology was performed and it revealed a secretory carcinoma. This tumor is morphologically characterized by the presence of abundant eosinophilic secretions in intracellular vacuoles and intercellular spaces. The objective of this article is to review the epidemiological and clinical aspect of secretory carcinoma from a case report and literature review.

Triple-Negative Breast Cancer Histological Subtypes with a Favourable Prognosis

“…Since the description of the initial series by McDivitt and Stewart, several hundred SCs have been reported, mostly as single case reports, small single institutional series and two larger database analyses [ 138 , 139 ]. These are summarized in Supplementary Table S6 [ 124 , 125 , 127 , 129 , 130 , 131 , 132 , 138 , 139 , 140 , 141 , 142 , 143 , 144 , 145 , 146 , 147 , 148 ]. In 2018, Garlick reviewed 89 cases previously published and these are included in the table on the basis of his review [ 144 ].…”