Secretolithic Therapy of Acute Sinusitis

Рязанцев, С. В.; Krivopalov, A. A.; Шамкина, П. А.

doi:10.21518/2079-701x-2017-16-78-83

Cited by 4 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The high incidence of rhinosinusitis is associated with a number of negative factors: an increase in the number of viral diseases, an increase in antibiotic-resistant strains of bacteria, and a high incidence of immunodeficiency and allergic diseases. Moreover, inadequate treatment of inflammatory diseases of the nasal cavity and paranasal sinuses leads to an increase in the incidence of chronic processes, so it is necessary to be more careful in the selection and prescription of rational therapy for inflammatory processes in the nasal cavity and paranasal sinuses [4] Rеsults Аnd Disсussiоn Acute inflammation of the mucous membrane is accompanied by a pronounced pathomorphological process, which includes tissue, cellular and immune reactions. In the first hours and days of the disease, local treatment of acute rhinosinusitis is very important, which helps to quickly stop inflammation and achieve recovery without the use of systemic antibacterial drugs.…”

Section: Mаtеriаls аNd Mеthоdsmentioning

confidence: 99%

The Role of Local Therapy in The Treatment of Patients with Acute Rhinosinusitis in Outpatient Settings

Yunusova Z.V.,

Kasimova N.D.

2023

Texa. Jour. of Medi. Scie.

View full text Add to dashboard Cite

Acute rhinosinusitis is one of the most common diseases encountered in the practice of an otorhinolaryngologist. The frequency of visits from patients with acute rhinosinusitis is increasing both in outpatient and inpatient practice. Despite the development of modern medicine, the relevance of the problem of this disease is growing every year, and this has a number of reasons. In the first hours and days of the disease, local treatment is very important, which helps to quickly stop inflammation and achieve recovery without the use of systemic antibacterial drugs

show abstract

Section: Mаtеriаls аNd Mеthоdsmentioning

confidence: 99%

The Role of Local Therapy in The Treatment of Patients with Acute Rhinosinusitis in Outpatient Settings

Yunusova Z.V.,

Kasimova N.D.

2023

Texa. Jour. of Medi. Scie.

View full text Add to dashboard Cite

show abstract

“…A prolonged overload of the ciliated epithelium causes its dystrophy and atrophy. The vicious circle of ARS pathogenesis is closed [4,5].…”

Section: Issn 1562-725x (Print) Issn 2518-1572 (Online)mentioning

confidence: 99%

“…from the beginning of its use in Germany. At the moment, Sinupret ® is one of the most studied herbal drugs both in the pharmacological experiment and clinical trials [4,5,8,9].…”

Section: Issn 1562-725x (Print) Issn 2518-1572 (Online)mentioning

confidence: 99%

“…Thanks to the unique combination of biologically active substances (BAS) of five medicinal plants Sinupret ® has a versatile complex action, breaking the "vicious circle" in RS. The pharmacodynamics of Sinupret ® includes such major effects as secretomotoric, secretolithic, anti-inflammatory, antiinfective and immunomodulating action [4,5,[8][9][10][11].…”

Section: Issn 1562-725x (Print) Issn 2518-1572 (Online)mentioning

confidence: 99%

See 1 more Smart Citation

The significance of selecting phytopreparations for individualized therapy of acute rhinosinusitis

et al. 2017

View full text Add to dashboard Cite

The article is devoted to modern approaches to the treatment of acute rhinosinusitis taking into account the basic principles of the rational pharmacotherapy. Today acute rhinosinusitis (ARS) remains in the leading position among other diseases in outpatient practice, therefore, the choice of the optimal treatment tactics and the optimal drug in each clinical case is of particular importance. The drugs of choice for acute uncomplicated rhinosinusitis are herbal preparations. The phytopreparations have an effect on all links of the pathogenesis of the disease due to the complex action of their biologically active substances. The phytopreparation Sinupret ® (Bionorica CE, Germany) is very often recommended by doctors and pharmacists for treating rhinitis, sinusitis and their complications. Priority of the choice of the drug is determined by its high efficiency and safety proven by numerous preclinical and clinical studies, the long experience of use and the presence of several dosage forms. Despite the common name each of the drugs of this brand has its own characteristics. They differ in the specificity of the dosage form, the physicochemical state of the active pharmaceutical substance, the dose of the active substances. Various Sinupret ® modifications are important for the individualized rational pharmacotherapy of patients with ARS provided by both a physician and a pharmacist. When providing pharmaceutical care a pharmacist select over-the-counter medicines taking into account their effectiveness, safety, quality and economic expediency. Висвітлені сучасні підходи до лікування гострих риносинуситів, які ґрунтуються на основних принципах раціональ-ної фармакотерапії. Зважаючи на значну поширеність гострих риносинуситів, асоційованих з ГРВІ, особливого зна-чення набуває вибір оптимальної тактики лікування та оптимального лікарського препарату у кожній клініч-ній ситуації. Препаратами вибору при гострих неускладнених риносинуситах вважаються рослинні препарати, які за рахунок комплексної дії біологічно активних речовин впливають на усі ланки патогенезу захворювання. Найбільш рекомендованим лікарями та фармацевтами фітопрепаратом є Синупрет ® виробництва компанії Біонорика СЕ (Німеччина). Пріоритетність вибору препарату визначається його високою ефективністю та без-пекою, які підтверджуються результатами численних доклінічних і клінічних досліджень, тривалим досвідом застосування, наявністю декількох лікарських форм. Незважаючи на загальну назву, кожен з препаратів цього бренду має свої особливості, які визначаються специфікою лікарської форми, фізико-хімічним станом актив-ної фармацевтичної субстанції, дозою діючих речовин. Різномаїття модифікацій Синупрету ® є важливим ін-струментом забезпечення індивідуалізованої раціональної фармакотерапії хворих на риносинусит не лише лікарем, але й фармацевтичним працівником, який у межах фармацевтичної опіки здійснює вибір безрецеп-турних лікарських препаратів з урахуванням їхньої ефективності, безпеки, якості та економічної доцільності. Ключові слова: гострий риносинусит...

show abstract

Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis

et al. 2020

Self Cite

View full text Add to dashboard Cite

Today, acute rhinosinusitis is one of the most common infectious diseases in the world. Usually, acute rhinosinusitis develops against the background of acute respiratory viral infection caused by influenza viruses, parainfluenza, respiratory syncytial virus, adenoviruses, or rhinoviruses. At the same time, in 1–2% of cases, the course of acute respiratory viral infection is complicated by bacterial sinusitis. At the same time, in 1–2% of cases, the course of acute respiratory viral infection is complicated by bacterial sinusitis. Considering the stages of the process, it is extremely important to adequately prescribe therapy at the onset of acute respiratory viral infection before the development of symptoms of acute rhinosinusitis, since the prognosis largely depends on its effectiveness. Treatment of acute rhinosinusitis is aimed at relieving the symptoms of the disease, improving aeration of the nasal cavity and paranasal sinuses, restoring the functions of mucociliary transport, and in the case of bacterial agent attachment, at the eradication of the pathogen. Such problems are solved through complex therapy, including irrigation measures, decongestants, topical glucocorticosteroids, and antibiotics if indicated. To improve the function of mucociliary transport the standard therapy of acute rhinosinusitis is combined with herbal medicines, which have a mucoactive, secretomotor, secretolytic and anti-inflammatory effects. The article presents data on the pharmacokinetics and pharmacodynamics of the drug Sinupret, the results of experimental studies and clinical studies that prove the high effectiveness and safety of the drug in the complex treatment of acute rhinosinusitis. One of the important advantages of using the herbal drug Sinupret is an increase the effectiveness of antibiotic therapy, which allows for a faster recovery in bacterial sinusitis, and moreover in cases of acute post-viral sinusitis, Sinupret can be used as monotherapy.

show abstract

Secretolithic Therapy of Acute Sinusitis

Cited by 4 publications

References 11 publications

The Role of Local Therapy in The Treatment of Patients with Acute Rhinosinusitis in Outpatient Settings

The Role of Local Therapy in The Treatment of Patients with Acute Rhinosinusitis in Outpatient Settings

The significance of selecting phytopreparations for individualized therapy of acute rhinosinusitis

Highlights of prescribing herbal medicines in the complex therapy of acute rhinosinusitis

Contact Info

Product

Resources

About