Abstract:In response to microbiota colonization, the intestinal epithelia of many animals exhibit increased rates of cell proliferation. We used gnotobiotic larval zebrafish to identify a secreted factor from the mutualist
Aeromonas veronii
that is sufficient to promote intestinal epithelial cell proliferation. This secreted
A. veronii
protein is a homologue of the
Vibrio cholerae
GlcNAc binding protein GbpA, which was identified as a chitin-binding c… Show more
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