Secondary Syphilis and Sarcoidosis

McMillan, Gary L.

doi:10.1001/archderm.1975.01630140122018

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…Of note, secondary syphilis has been shown to mimic sarcoidosis; however, the patient's treponema antibody previously was negative. 11 In addition, it was considered that there are a few cases in the literature of tattoos that have occasionally produced a granulomatous sarcoid-like pathology; however, biopsy of the forearm was not taken on the tattoo site and scalp biopsy results showed evidence of coexisting pathologies. 12 Typically, in these instances, the correct diagnosis is discovered on H&E, where an abundance of noncaseating granulomas with sparse surrounding infiltrate can be visualized filling the dermis and sometimes obliterating follicular structures.…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis Coexisting With Distinct Forms of Alopecia on the Scalp: A Case Series

Sode

Ogwumike

Hosler

et al. 2023

The American Journal of Dermatopathology

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Sarcoidosis is an idiopathic multisystem inflammatory disease that can affect virtually any part of the body. Often, it can initially present solely in the skin. Histologically, it is characterized by noncaseating, 'naked' granulomas in the dermis and subcutaneous tissue. Clinically, sarcoidosis is often referred to as a 'mimicker' of many other pathologic processes because of its wide array of presentations. Occasionally, sarcoidosis can present in the scalp as both a scarring and nonscarring alopecia. There are countless reports of sarcoidosis mimicking various other alopecias including acne keloidalis nuchae, discoid lupus erythematosus, frontal fibrosing alopecia, lichen planopilaris, and alopecia areata totalis. In this case series, we present 2 novel cases of sarcoidosis not just clinically mimicking other forms of alopecia but occurring in conjunction with a separate and histologically distinct primary alopecia.

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Section: Discussionmentioning

confidence: 99%

Sarcoidosis Coexisting With Distinct Forms of Alopecia on the Scalp: A Case Series

Sode

Ogwumike

Hosler

et al. 2023

The American Journal of Dermatopathology

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Secondary Pulmonary Syphilis: Report of A Likely Case and Literature Review

David

Perpoint

Boibieux

et al. 2006

Clinical Infectious Diseases

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We report the case of a homosexual, HIV-positive man with typical secondary syphilis and multiple excavated pulmonary subpleural nodules. Syphilis with direct pulmonary involvement was suggested by a positive result of PCR of a bronchoalveolar lavage fluid specimen, then confirmed by a positive therapeutic test result. Only 9 reports of pulmonary involvement in secondary syphilis have been reported to date in the English-language literature. Clinicians should be aware of this atypical localization of syphilis.

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Secondary Syphilis and Sarcoidosis

Cited by 2 publications

References 6 publications

Sarcoidosis Coexisting With Distinct Forms of Alopecia on the Scalp: A Case Series

Sarcoidosis Coexisting With Distinct Forms of Alopecia on the Scalp: A Case Series

Secondary Pulmonary Syphilis: Report of A Likely Case and Literature Review

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